2019.01至今：中国农业大学 教授、青年科学家创新团队负责人

2015.04-2018.12：中国农业大学 副教授

2013.08-2015.04：曼彻斯特大学 合成化学博士后

2009.09-2013.07：诺丁汉大学 合成化学博士

2005.09-2009.07：中国农业大学 理学学士

1. 新材料与人类健康

利用Click Chemistry，光催化反应等最新合成技术制备生物医用材料和具有特殊功能的表面材料；研究内容涉及：组织修复水凝胶材料、柔性可植入智能材料、抗菌表面材料、超疏水表面材料等。

2. 绿色化学与药物研发

建立符合绿色化学理念的新型合成方法，特别是新型氘标记化合物合成方法；并以新型合成方法为基础开发氘代药物及疾病诊断试剂。

更多信息见：https://ajresearchgroup.com/

1. 2019-2021，北京市自然科学基金，铁催化氧化还原缩合反应的建立及其在苯并咪唑、喹唑啉类药物合成中的应用，主持

2. 2018-2021，国家重点研发计划，靶标导向的分子设计与天然产物结构多样性衍生

3. 2017-2019，国际合作项目，新兴金属有机框架/石墨烯杂化复合材料的开发，主

2016-2019，国家自然科学基金项目，建立绿色无氨伯奇还原反应——新型电子盐体系的探索与应用，主持

论文

1. In press, Luo, T.; Li, L.; Chen, Y.; An, J.*; Liu, C.; Yan, Z.; Carter, J. H.; Han, X.; Sheveleva, A. M.; Tuna, F.; McInnes, E. J. L.; Tang, C. C.; Schröder, M.*; Yang, S.* Construction of C-C bonds via photoreductive coupling of ketones and aldehydes in the metalorganic-framework MFM-300(Cr), Nature Communications

2. Li, H.; Peng, M.; Lai, Z.; Ning, L.; Chen, X.; Zhang, X.; Wang, P.; Szostak, R.; Szostak, M.*; An, J.* Acyl Fluorides as Direct Precursors to Fluoride Ketyl Radicals: Reductive Deuteration using SmI₂ and D₂O. Chem. Comm. 2021, doi.org/10.1039/D1CC01381E

3. Ning, L.; Li, H; Lai, Z.; Szostak, M.; Chen, X.; Dong, Y.*; Jin, S.; An, J.* Synthesis of α‑Deuterated Primary Amines via Reductive Deuteration of Oximes Using D₂O as a Deuterium Source. J. Org. Chem. 2021, 86, 2907-2916.

4. Luo, S.; Weng, C.; Ding, Y.; Ling, C.; Szostak, M.; Ma, X.*; An, J.* Reductive Deuteration of Aromatic Esters for the Synthesis of α,α-Dideuterio Benzyl Alcohols Using D₂O as Deuterium Source. Synlett 2021. 32(01), 51-56.

5. Li, H.; Hou, Y.; Liu, C.; Lai, Z.; Ning, L.; Szostak, R.; Szostak, M.*; An, J.* Pentafluorophenyl Esters: Highly Chemoselective Ketyl Precursors for the Synthesis of α,α-Dideuterio Alcohols Using SmI₂ and D₂O as a Deuterium Source. Org. Lett. 2020, 22 (4), 1249–1253.

6.  Fan, X.; Han, M.; Ding, Y.; Zhang, X.; Li, H.*; An, J.* Synthesis and fungicidal activity of deuterated pefurazoate. Chinese Journal of Pesticide Science. 2020, 22 (1), 27-34.

7. Lei, P.; Ling, Y.; An, J.; Nolan, S. P.; Szostak, M. Adv. Synth. Catal. 2019, 361 (24), 5654.

8. Ding, Y.; Luo, S.; Ma, L.*; An, J.* Reductive Cleavage of Unactivated Carbon–Cyano Bonds under Ammonia-Free Birch Conditions. J. Org. Chem. 2019, 84 (24), 15827–15833.

9. Ding, Y.; Luo, S.; Weng, C.; An, J.* Reductive Deuteration of Nitriles Using D₂O as a Deuterium Source. J. Org. Chem. 2019, 84 (23), 15098–15105.

https://www.organic-chemistry.org/abstracts/lit6/533.shtm

10. Li, H; Lai, Z.; Adijiang, A.; Zhao, H.; An, J.* Selective C-N σ Bond Cleavage in Azetidinyl Amides under Transition Metal-Free Conditions. Molecules 2019, 24 (3), 459.

Invited contribution to a special edition “amide bond activation”; guest editor: Prof. Dr. Michal Szostak.

11. Ding, Y.; Luo, S.; Adijiang, A.; Zhao, H.; An, J.* Reductive Deuteration of Nitriles: The Synthesis of α,α-Dideuterio Amines by Sodium-Mediated Electron Transfer Reactions. J. Org. Chem. 2018, 83 (19), 12269-12274.

12. Lei, P.; Ding, Y.; Zhang, X.; Adijiang, A.; Li, H.; Ling, Y.; An, J.* A Practical and Chemoselective Ammonia-Free Birch Reduction. Org. Lett. 2018, 20, 3439-3442.

13. Zhang, B.; Li, H.; Ding, Y.; Yan, Y.; An, J.* Reduction and Reductive Deuteration of Tertiary Amides Mediated by Sodium Dispersions with Distinct Proton Donor-Dependent Chemoselectivity. J. Org. Chem. 2018, 83 (11), 6006–6014.

https://www.organic-chemistry.org/abstracts/lit6/358.shtm

14. Han, M.; Ding, Y.; Yan, Y.; Li, H.; Luo, S.; Adijiang, A.; Ling, Y.; An, J.* Transition-Metal-Free, Selective Reductive Deuteration of Terminal Alkynes with Sodium Dispersions and EtOD ‑ d 1. Org. Lett. 2018, 20, 8–11.

15. Lei, P.; Meng, G.; Shi, S.; Ling, Y.; An, J.; Szostak, R.; Szostak, M.* Suzuki–Miyaura Cross-Coupling of Amides and Esters at Room Temperature: Correlation with Barriers to Rotation around C–N and C–O Bonds. Chem. Sci. 2017, 8, 6525–6530.

https://www.organic-chemistry.org/abstracts/lit6/375.shtm

16. Lei, P.; Meng, G.; Ling, Y.; An, J.; Szostak, M.* Pd-PEPPSI: Pd-NHC Precatalyst for Suzuki-Miyaura Cross-Coupling Reactions of Amides. J. Org. Chem. 2017, 82 (13), 6638–6646.

17. Lei, P.; Meng, G.; Ling, Y.; An, J.; Nolan, S. P.; Szostak, M.* General Method for the Suzuki-Miyaura Cross-Coupling of Primary Amide-Derived Electrophiles Enabled by [Pd(NHC)(Cin)Cl] at Room Temperature. Org. Lett. 2017, 19 (24), 6510–6513.

18. Li, H.; Zhang, B.; Dong, Y.; Liu, T.; Zhang, Y.; Nie, H.; Yang, R.; Ma, X.; Ling, Y.; An, J.* A Selective and Cost-Effective Method for the Reductive Deuteration of Activated Alkenes. Tetrahedron Lett. 2017, 58 (28), 2757–2760.

19. Han, M.; Ma, X.; Yao, S.; Ding, Y.; Yan, Z.; Adijiang, A.; Wu, Y.; Li, H.; Zhang, Y.; Lei, P.; An, J.* Development of a Modified Bouveault–Blanc Reduction for the Selective Synthesis of α,α-Dideuterio Alcohols. J. Org. Chem. 2017, 82 (2), 1285–1290.

https://www.organic-chemistry.org/abstracts/lit5/727.shtm

20. Fearnley, A. F.; An, J.; Jackson, M.; Lindovska, P.; Denton, R. M.* Synthesis of Quaternary Aryl Phosphonium Salts: Photoredox-Mediated Phosphine Arylation. Chem. Commun. 2016, 52 (28), 4987–4990.

21. An, J.; Work, D. N.; Kenyon, C.; Procter, D. J.* Evaluating a Sodium Dispersion Reagent for the Bouveault-Blanc Reduction of Esters. J. Org. Chem. 2014, 79 (14), 6743–6747.

22. An, J.; Denton, R. M.*; Lambert, T. H.*; Nacsa, E. D. The Development of Catalytic Nucleophilic Substitution Reactions: Challenges, Progress and Future Directions. Org. Biomol. Chem. 2014, 12 (19), 2993.

23. Tang, X.; An, J.; Denton, R. M.* A Procedure for Appel Halogenations and Dehydrations Using a Polystyrene Supported Phosphine Oxide. Tetrahedron Lett. 2014, 55 (4), 799–802.

24. An, J.; Denton, R. M. Heteroatom Methods. Annu. Reports Sect. “B” (Organic Chem. 2013, 109, 167.

25. An, J.; Tang, X.; Moore, J.; Lewis, W.; Denton, R. M. Phosphorus(V)-Catalyzed Deoxydichlorination Reactions of Aldehydes. Tetrahedron 2013, 69 (41), 8769–8776.

26. Denton, R. M.*; An, J.; Lindovska, P.; Lewis, W. Phosphonium Salt-Catalysed Synthesis of Nitriles from in Situ Activated Oximes. Tetrahedron 2012, 68 (13), 2899–2905.

27. Denton, R. M.*; An, J.; Adeniran, B.; Blake, A. J.; Lewis, W.; Poulton, A. M. Catalytic Phosphorus ( V ) -Mediated Nucleophilic Substitution Reactions : Development of a Catalytic Appel Reaction. J. Org. Chem. 2011, 76 (V), 6749–6767.

28. Denton, R. M.*; An, J.; Adeniran, B. Phosphine Oxide-Catalysed Chlorination Reactions of Alcohols under Appel Conditions. Chem Commun 2010, 46, 3025–3027.

专利

1、一种α-一氘代醇类化合物、氘代药物的合成方法，2021，202110150475.9，发明专利

2、一种α-一氘代胺类化合物、氘代药物及其制备方法，2021，202110038949.0，发明专利

3、一种高选择性的还原脱氰基反应，2019，201911025946.2，发明专利

4、一种N-正丙基酰胺的合成方法，2018，201811572572.1，发明专利

5、一种苯并咪唑类化合物合成方法，2018，201810789392.2，发明专利

6、氘代戊4-烯基-N-糠基-N-咪唑-1-基羰基-DL-高丙氨酸酯制备及杀菌活性，2018，201810360623.8，发明专利

7、一种将叔酰胺还原为醇和/或胺的方法，2018，201810053986.7，发明专利

8、一种新型电子盐体系以及不饱和烃类化合物的还原方法，2017，201710059952.4，发明专利

9、一种α, α‐二氘代醇类化合物的合成方法，2016，201610382079.8，发明专利

10、一种炔烃、腈及有机卤化物的还原氘化方法，发明专利

11、一种基于铁催化氧化还原偶联反应的苯并咪唑类化合物合成方法，发明专利

12、一种酰氟类化合物还原氘化合成α, α-二氘代醇、氘代药物的方法，发明专利