
2026.05-至今:中国农业大学,营养与健康系,教授
2020.07-2026.04:中国农业大学,营养与健康系,副教授
2019.04-2020.07:华盛顿州立大学,博士后
2016.03-2019.03:中国农业大学,北京食品营养与人类健康高精尖创新中心,岗位科学家
2013.07-2016.02:国家粮食局科学研究院,助理研究员、副研究员
2008.09-2013.06:中国农业大学,工学博士
2004.09-2008.06:天津大学,工学学士
功能基料挖掘与评价(大脑认知、肠道健康、糖脂代谢等)
1. 科技部,全谷物健康食品创制与应用示范,主持
2. 科技部,蛋黄磷脂组分的功能挖掘与高端配料创制,主持
3. 国家自然科学基金委,β-棕榈酸调控肠道干细胞分化的分子机制,主持
4. 北京市科委,耗竭型CD4+T细胞驱动免疫衰老的分子机制及其营养干预研究,主持
5. 北京市科委,精准靶向残留农药肠道损伤的益生菌筛选及产品开发技术,主持
6. 省、市、自治区科技项目,益生菌发酵乳调控肠脑轴机制解析,主持
7. 企业横向项目,婴幼儿配方奶粉体外模拟消化及肠道健康评价,主持
8. 企业横向项目,益生菌生产关键工艺技术攻关,主持
9. 企业横向项目,靶向肥胖人群的全谷物米饭创制及其风味分析,主持
10. 企业横向项目,裸藻多糖改善动脉粥样硬化功效评价,主持
一、发表文章
1. Le Cheng, Ming Zhang, Fang Wu, Jianguo Dong, Yifei Wang, Lin Dong, Yumeng Ma, Chenyan Zheng, Zihan Wang, Yixuan Li, Ran Wang, Fazheng Ren, Bing Fang*. Low-cholesterol egg yolk lipids alleviated the development of atherosclerosis in ApoE -/- mice by regulating bile acid metabolism and gut microbiota. Food Research International, 2026, 223(1): 117906.
2. Wen Zhao, Mingkun Liu, Hanglian Lan, Ran Wang, Wei-Lian Hung, Jian He, Bing Fang*. Modulation of intestinal smooth muscle cell function by bl-99 postbiotics in functional constipation. Foods, 2025, 14(19): 3441.
3. Le Cheng, Ming Zhang, Lin Dong, Yifei Wang, Jianguo Dong, Fang Wu, Chenyan Zheng, Yumeng Ma, Zihan Wang, Ran Wang, Yixuan Li, Bing Fang*. Interaction between hyaluronic acid and phospholipid bilayer and its influence on stability and bioavailability of luteolin-loaded liposomes. Food Chemistry-X, 2025, 31: 103116.
4. Yumeng Ma, Ming Zhang, Yutong Jin, Yifei Wang, Tengteng Ji, Fang Wu, Yixuan Li, Ran Wang, Huiyuan Guo, Fazheng Ren, Bing Fang*. 2'-Fucosyllactose ameliorates cognitive impairment and neuroinflammation in AD mice. Journal of Agricultural and Food Chemistry, 2025, 73(41): 26073-26086.
5. Xinlei Yuan#, Zihan Wang#, Fang Wu, Le Cheng, Yutong Jin, Jianguo Dong, Chenyan Zheng, Yumeng Ma, Yan Jin, Bing Fang*. The impact of imidacloprid in dietary residues on intestinal damage and the increased risk of Enterotoxigenic Escherichia coli infection. Foods, 2025, 14(12): 2119.
6. Tengteng Ji, Bing Fang*, Ming Zhang, Le Cheng, Xinlei Yuan, Yutong Jin, Fang Wu, Chenyan Zheng, Yumeng Ma. Oat beta-glucan inhibited obesity in mice though stem cell remodeling. International Journal of Biological Macromolecules, 2025, 311(2): 143747.
7. Xinlei Yuan, Fang Wu, Le Cheng, Tengteng Ji, Chenyan Zheng, Yumeng Ma, Yutong Jin, Jianguo Dong, Yan Jin, Bing Fang*. Chlorpyrifos inhibits intestinal stem cell proliferation and differentiation at the acceptable daily intake and disrupts immune responses at high doses. Journal of Agricultural and Food Chemistry, 2025, 73(20): 12455-12464.
8. Fang Wu, Yaqiong Liu, Ming Zhang, Xinlei Yuan, Yutong Jin, Yixuan Li, Ran Wang, Yanling Hao, Bing Fang*. Effects of 1,3-dioleoyl-2-palmitoylglycerol on intestine structural and functional development in early-life. Molecular Nutrition & Food Research, 2025, e70051.
9. Le Cheng, Xinlei Yuan, Ming Zhang, Jianguo Dong, Yao Wu, Rang Wang, Yixuan Li, Lishui Chen, Bing Fang*. Characterization of phospholipid profiles of egg yolks: Newly classified plasmalogens, distribution of polyunsaturated fatty acids, and the effects of dietary enrichment.Food Chemistry: X, 2025, 25: 102105.
10. Jianmin Wu#, Ming Zhang#, Hao Zhang#, Mingxuan Sheng, Jiazeng Sun, Fang Wu, Haina Gao, Lishui Chen, Zhili Li, Qiyu Tian, Longjiao Zhu, Bing Fang*. PMN-MDSC: a culprit behind immunosenescence and increased susceptibility to clostridioides difficile infection during aging. Engineering, 2024, 42: 59-73.
11. Yaqiong Liu#, Fang Wu#, Ming Zhang, Yutong Jin, Xinlei Yuan, Yanling Hao, Li-shui Chen, Bing Fang *. 2’-Fucosyllactose and 3’-sialyllactose reduce mortality in neonatal enteroaggregative Escherichia coli infection by improving the construction of intestinal mucosal immunity. Journal of Agricultural and Food Chemistry, 2024, 72(47): 26165-26177.
12. Tengteng Ji, Bing Fang *, Yutong Jin, Chenyan Zheng, Xinlei Yuan, Jianguo Dong, Le Cheng, Fang Wu. Euglena attenuates high-fat diet induced obesity and especially glucose intolerance. Nutrients, 2024, 16(21), 3780.
13. Bing Fang, Chenyan Zheng, Yumeng Ma, Fang Wu, Le Cheng, Yixuan Li, Ran Wang, Fazheng Ren*. Inhibited adipogenesis and low-grade inflammation enhance adipocyte hypertrophy in aging adipose tissue. Food, Nutrition and Health, 2024, 1: 2.
14. Fang Wu, Yaqiong Liu, Ming Zhang, Xinlei Yuan, Tengteng Ji, Yutong Jin, Yixuan Li, Ran Wang, Yanling Hao, Bing Fang*. Effects of 1-oleate-2-palmitate-3-linoleate glycerol supplementation on the small intestinal development and gut microbial composition of neonatal mice. Food Research International, 2024, 195: 114993.
15. Zhe Sun#, Bing Fang#, Haina Gao, Yuhang Sun, Yue Liu, Huiyuan Guo, Liang Zhao, Fazheng Ren, Ming Zhang*. A gut-brain connection: probiotics L9 and A6 offer new insights into AD prevention. Food Science and Human Wellness, 2024, accept.
16. Fang Wu, Yaqiong Liu, Ming Zhang, Xinlei Yuan, Tengteng Ji, Yutong Jin, Yixuan Li, Ran Wang, Yanling Hao, Bing Fang*. Effects of 1-oleate-2-palmitate-3-linoleate glycerol supplementation on the small intestinal development and gut microbial composition of neonatal mice. Food Research International, 2024, 195: 114993.
17. Le Cheng, Tengteng Ji, Ming Zhang, Bing Fang*. Recent advances in squalene: Biological activities, sources, extraction, and delivery systems. Trends in Food Science & Technology, 2024, 146: 104392.
18. Haina Gao#, Bing Fang#, Zhe Sun, Xiaoyu Du, Huiyuan Guo, Liang Zhao, Ming Zhang*. Effect of human milk oligosaccharides on learning and memory in mice with Alzheimer’s disease. Journal of Agricultural and Food Chemistry, 2024, 72, 1067-1081.
19. Wei Xiong#, Bing Fang#, Xiaoyu Wang, Ming Zhang, Min Du, Jiazeng Sun, Juan Chen, Yixuan Li, Changhao Sun, Xingen Lei, Xue Zhang, Fazheng Ren*. Dietary lipid Intervention in the prevention of brain aging. Engineering, 2024, 37(6): 130-139.
20. Tengteng Ji, Bing Fang*, Fang Wu, Yaqiong Liu, Le Cheng, Yixuan Li, Ran Wang, Longjiao Zhu. Diet change improves obesity and lipid deposition in high-fat diet-induced mice. Nutrients, 2023, 15: 4978.
21. Tengteng Ji, Bing Fang*, Ming Zhang, Yaqiong Liu. Succinate enhances lipolysis and decreases adipocytes size in both subcutaneous and visceral adipose tissue from high-fat-diet-fed obese mice. Foods, 2023, 12: 4285.
22. Bing Fang#, Yixuan Li#, Fazheng Ren*. Chiral nanoparticles as adjuvants for vaccines. Chem, 2022, 8: 1-3.
23. Guo-ping Zhao, Jin-wang Li, Fang-wei Yang, Xue-feng Yin, Fa-zheng Ren, Bing Fang*, Guo-fang Pang*. Spermiogenesis toxicity of imidacloprid in rats, possible role of CYP3A4. Chemosphere, 2021, 282: 131120.
24. Fang-Wei Yang, Bing Fang*, Guo-Fang Pang, Ming Zhang, Fa-Zheng Ren. Triazophos and its metabolite diethyl phosphate have different effects on endocrine hormones and gut health in rats. Journal of Environmental Science and Health Part B, 2021, 56(6): 1-11.
25. 杨志轩, 方冰*, 任发政, 冷小京. 牛α-乳白蛋白-油酸复合物对肿瘤细胞能量代谢的影响. 中国食品学报, 2021, 21(1): 38-43 (EI).
26. Bing Fang*, Zhi-xuan Yang, Fa-zheng Ren. The self-assembled α-lactalbumin-oleic acid complex inhibits ATP supply from both glycolysis and the TCA cycle in HepG2 cells and HepG2-bearing nude mice. International Journal of Biological Macromolecules, 2020, 159: 258-263 (IF:6.953).
27. Yanan Sun, Zhixuan Yang, Fa Zheng Ren, Bing Fang*. FGF19 alleviates palmitate-induced atrophy in C2C12 cells by inhibiting mitochondrial overload and insulin resistance. International Journal of Biological Macromolecules, 2020, 158: 401-407 (IF:6.953).
28. Yanan Sun, Jiaqiang Huang, Zhongzhou Chen, Min Du, Fa Zheng Ren, Jie Luo*, Bing Fang*. Amyotrophy induced by a high-fat diet is closely related to inflammation and protein degradation determined by quantitative phosphoproteomic analysis in skeletal muscle of C57BL/6J mice. Journal of Nutrition, 2020, 150(2), 294-302 (IF:4.798).
二、奖励
1. 2024年度中国乳制品工业协会乳业优秀青年科技工作者
2. 第十三届大北农科学技术奖一等奖,1/13
3. 2023年度中国商业联合会科学技术奖特等奖,1/10
4. 2023年度中国乳制品工业协会技术发明奖二等奖, 1/10
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