2020.07-至今：中国农业大学，营养与健康系，副教授

2019.04-2020.07：华盛顿州立大学，博士后

2016.03-2019.03：中国农业大学，北京食品营养与人类健康高精尖创新中心，岗位科学家

2013.07-2016.02：国家粮食局科学研究院，助理研究员、副研究员

2008.09-2013.06：中国农业大学，工学博士

2004.09-2008.06：天津大学，工学学士

营养干预精准靶点挖掘与功能因子筛选

1. 科技部，全谷物健康食品创制与应用示范，主持

2. 科技部，蛋黄磷脂组分的功能挖掘与高端配料创制，主持

3. 国家自然科学基金委，“β-棕榈酸调控肠道干细胞分化的分子机制”，主持

4. 北京市科委“耗竭型CD4+ T细胞驱动免疫衰老得分子机制及其营养干预研究”，主持

5. 北京市科委“精准靶向残留农药肠道损伤的益生菌筛选及产品开发技术”，主持

6. 省、市、自治区科技项目”原料乳品质对鲜奶产品品质的影响规律及调控机制”，主持

7. 省、市、自治区科技项目”益生菌发酵乳对压力人群的改善作用及产品转化研究”，主持

8. 省、市、自治区科技项目“草原酸奶自主优良益生菌种的筛选及应用研究”，主持

9. 中荷奶业发展中心国际合作项目“中国原料乳中耐热芽孢杆菌的区域特性及控制方案研究”，主持

一、发表文章

1. Jianmin Wu#, Ming Zhang#, Hao Zhang#, Mingxuan Sheng, Jiazeng Sun, Fang Wu, Haina Gao, Lishui Chen, Zhili Li, Qiyu Tian, Longjiao Zhu, Bing Fang*. PMN-MDSC: a culprit behind immunosenescence and increased susceptibility to clostridioides difficile infection during aging. Engineering, 2024, accept.  

2. Zhe Sun#, Bing Fang#, Haina Gao, Yuhang Sun, Yue Liu, Huiyuan Guo, Liang Zhao, Fazheng Ren, Ming Zhang*. A gut-brain connection: probiotics L9 and A6 offer new insights into AD prevention. Food Science and Human Wellness, 2024, accept.

3. Fang Wu, Yaqiong Liu, Ming Zhang, Xinlei Yuan, Tengteng Ji, Yutong Jin, Yixuan Li, Ran Wang, Yanling Hao, Bing Fang*. Effects of 1-oleate-2-palmitate-3-linoleate glycerol supplementation on the small intestinal development and gut microbial composition of neonatal mice. Food Research International, 2024, 195: 114993.

4. Minghui Wang, Xiaoxuan Xu, Mingxuan Sheng, Ming Zhang, Fang Wu, Zhi Zhao, Meng Guo, Bing Fang*, Jianmin Wu*. Tannic acid protects against colitis by regulating the IL17 - NFκB and microbiota - methylation pathways. International Journal of Biological Macromolecules, 2024, 274(Pt 1): 133334.

5. Le Cheng, Tengteng Ji, Ming Zhang, Bing Fang*. Recent advances in squalene: Biological activities, sources, extraction, and delivery systems. Trends in Food Science & Technology, 2024, 146: 104392.

6. Haina Gao^#, Bing Fang^#, Zhe Sun, Xiaoyu Du, Huiyuan Guo, Liang Zhao, Ming Zhang*. Effect of human milk oligosaccharides on learning and memory in mice with Alzheimer’s disease. Journal of Agricultural and Food Chemistry, 2024, 72, 1067-1081.

7. Wei Xiong^#, Bing Fang^#, Xiaoyu Wang, Ming Zhang, Min Du, Jiazeng Sun, Juan Chen, Yixuan Li, Changhao Sun, Xingen Lei, Xue Zhang, Fazheng Ren*. Dietary lipid Intervention in the prevention of brain aging. Engineering, 2024, 37(6): 130-139.

8. Tengteng Ji, Bing Fang*, Fang Wu, Yaqiong Liu, Le Cheng, Yixuan Li, Ran Wang, Longjiao Zhu. Diet change improves obesity and lipid deposition in high-fat diet-induced mice. Nutrients 2023, 15, 4978.

9. Tengteng Ji, Bing Fang*, Ming Zhang, Yaqiong Liu. Succinate enhances lipolysis and decreases adipocytes size in both subcutaneous and visceral adipose tissue from high-fat-diet-fed obese mice. Foods 2023, 12, 4285.

10. Bing Fang^#, Yixuan Li^#, Fazheng Ren*. Chiral nanoparticles as adjuvants for vaccines. Chem, 2022, 8: 1-3.

11. Guo-ping Zhao, Jin-wang Li, Fang-wei Yang, Xue-feng Yin, Fa-zheng Ren, Bing Fang*, Guo-fang Pang*. Spermiogenesis toxicity of imidacloprid in rats, possible role of CYP3A4. Chemosphere, 2021, 282: 131120.

12. Fang-Wei Yang, Bing Fang*, Guo-Fang Pang, Ming Zhang, Fa-Zheng Ren. Triazophos and its metabolite diethyl phosphate have different effects on endocrine hormones and gut health in rats. Journal of Environmental Science and Health Part B, 2021, 56(6): 1-11.

13. 杨志轩, 方冰*, 任发政, 冷小京. 牛α-乳白蛋白-油酸复合物对肿瘤细胞能量代谢的影响. 中国食品学报, 2021, 21(1): 38-43.

14. Bing Fang*, Zhi-xuan Yang, Fa-zheng Ren. The self-assembled α-lactalbumin-oleic acid complex inhibits ATP supply from both glycolysis and the TCA cycle in HepG2 cells and HepG2-bearing nude mice. International Journal of Biological Macromolecules, 2020, 159: 258-263.

15. Sun, Y., Yang, Z., Ren, F.Z., Fang, B*. FGF19 alleviates palmitate-induced atrophy in C2C12 cells by inhibiting mitochondrial overload and insulin resistance. International Journal of Biological Macromolecules, 2020, 158: 401-407.  

16. Sun, Y., Huang, J., Chen, Z., Du, M., Ren, F.Z., Luo, J.*, Fang, B*. Amyotrophy induced by a high-fat diet is closely related to inflammation and protein degradation determined by quantitative phosphoproteomic analysis in skeletal muscle of C57BL/6J mice. The Journal of Nutrition, 2020, 150(2), 294-302.

17. 方冰*, 董立杰, 任发政, 周晓娟, 葛绍阳. 益生菌骆驼乳粉对II型糖尿病患者的辅助降糖作用. 中国乳品工业, 2020, 48(6): 14-17.

18. Li, J.W., Fang, B.*, Pang, G.F., Zhang, M., Ren, F.Z. Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. Pesticide Biochemistry and Physiology, 2019, 59, 68-79.

19. Yang, F.W., Fang, B.*, Pang, G.F., Ren, F.Z. Organophosphorus pesticide triazophos: a new endocrine disruptor chemical of hypothalamus-pituitary- adrenal axis. Pesticide Biochemistry and Physiology, 2019, 59, 91-97.

20. Li, J.W., Pang, G.F., Ren, F.Z., Fang, B*. Chlorpyrifos-induced reproductive toxicity in rats could be partly relieved under high-fat diet. Chemosphere, 2019, 229, 94-102.

21. Xing, H.Z., Fang, B.*, Pang, G.F., Ren, F.Z. 3-Monochloropropane-1, 2-diol causes irreversible damage to reproductive ability independent of hormone changes in adult male rats. Food and Chemical Toxicology, 2019, 124, 10-16.

22. 方冰, 张昊, 郭慧媛, 任发政*. 毛细管区带电泳在牛乳蛋白掺假检测中的应用及方法优化. 中国食品学报, 2019, 19(3): 289-298 (EI).

23. Yang, F.W., Li, J.W., Pang, G.F., Ren, F.Z., Fang, B*. Effects of diethyl phosphate, a non-specific metabolite of organophosphorus pesticides, on serum lipid, hormones, inflammation, and gut microbiota. Molecules, 2019, 24, 2003.

二、奖励

1. 2024年度中国乳制品工业协会乳业优秀青年科技工作者

2. 2023年度中国商业联合会科学技术奖特等奖，1/10

3. 2023年度中国乳制品工业协会技术发明奖二等奖， 1/10