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师资力量

  • 姓  名:詹菁
  • 性  别:女
  • 职  称:副教授
  • 所在系别:营养与健康系
  • 办公地点:中国农业大学建大校区1号楼
  • 电子邮箱:jingzhan@cau.edu.cn
个人简历

2021.06-至今:中国农业大学,优秀人才引进,副教授

2019.07-2021.05:中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,博士后

2014.08-2019.06:中国农业大学,理学院,理学博士

2010.08-2014.06:中国农业大学,理学院,理学学士


研究方向

1. 食源性化学物质对肠道菌群和肠道健康的影响

2. 环境污染物的健康效应与毒理学机制

3. 益生菌/益生元对人体健康的调节及作用机理


课题项目

1. 国家自然科学基金青年基金项目“晚期糖基化终产物-羧甲基赖氨酸(AGEs-CML)对肠道屏障的损伤及机制研究”,2023-2025年,主持。

2. 中国农业大学基础与前沿交叉研究专项“新型全氟化合物的肠道毒性筛查与评估”,2024.01-2024.12,主持。

3. 国家重点研发计划课题“冷链食品储运过程化学危害阻控关键技术研发及评价”,2022-2026年,项目骨干。

4. 中国农业大学青年科学家培育专项“典型芳香基有机磷酸酯阻燃剂的早期暴露特征研究”,2023-2024年,参与。

5. 中国博士后科学基金面上项目“红细胞介导的大气细颗粒物诱发血栓的机理研究”,2020-2021年,主持。

6. 国家重点研发计划课题“高风险农兽药化学污染物在慢性疾病发生发展中的作用机制研究”,2019-2022年,参与。


论文著作

1. Wang, X.Y.#, Lv, Y.C.#, Qiang, X., Liang, S.M., Li, R.S., Zhan, J.*, Liu, J.Y.*. Perfluorooctanoic acid (PFOA) and its alternative perfluorobutanoic acid (PFBA) alter hepatic bile acid profiles via different pathways. Science of The Total Environment, 2024, 950, 175312.

2. Qiang, X., Liang, S.M., Lv, Y.C., Wang, X.Y., Zhang. H., Zhan, J.*. Advanced glycation end products (AGEs) impair the intestinal epithelial barrier via STAT3 activation mediated by macrophages. Food and Chemical Toxicology, 2024, 192, 114966.

3. Zhan, J., Liu, S.Q.*, Zhang, Y.Z., Sun, Z.D., Zhou, Q.F., Jiang, G.J. Silica nanoparticles trigger phosphatidylserine exposure in red blood cells and induce thrombosis risk. Environmental Pollution, 2023, 327, 121591.

4. Niu, X.K., Zhang, N.N., Li, S.S., Li, N., Wang, R., Zhang, Q., He, J.J., Sun, E., Kang, X.H. *, Zhan, J*. Bifidobacterium animalis subsp. lactis MN-Gup protects miceagainst gut microbiota-related obesity and endotoxemia induced by a high fat diet. Frontiers in Nutrition, 2022, 9, 992947.

5. Wang, C.Y., Li, S.S., Sun, E.N., Xiao, R., Wang, R., Ren Y.M., He, J.J., Zhang, Q., Zhan, J*. Effects of fermented milk containing bifidobacterium animalis subsp. lactis MN‐Gup (MN‐Gup) and MN‐Gup‐Based synbiotics on obesity induced by high fat diet in rats. Nutrients, 2022, 14, 2631.

6. Xiao, R., Wang, R., Li S.S., Kang, X.H., Ren Y.M., Sun, E.N., Wang, C.Y., He, J.J., Zhan, J*. Preliminary evaluation of potential properties of three probiotics and their combination with prebiotics on GLP-1 secretion and type 2 diabetes alleviation. Journal of Food Quality, 2022, 2022, 8586843.

7. Zhan, J., Liu, S.Q.*, Sun, Z.D., Zhou, Q.F., Hu, L.G., Qu, G.B., Zhang, J.Q., Zhao, B., Jiang, G.J. Environmental impacts on the transmission and evolution of COVID-19 combing the knowledge of pathogenic respiratory coronaviruses. Environmental Pollution, 2020, 267, 115621.

8. Zhan, J., Ma, X.R., Liu, D.H., Liang, Y.R., Li, P.Z., Cui, J.N., Zhou, Z.Q., Wang, P*. Gut microbiome alterations induced by tributyltin exposure are associated with increased body weight, impaired glucose and insulin homeostasis and endocrine disruption in mice. Environmental Pollution, 2020, 266, 115276.

9. Zhan, J., Liang, Y.R., Liu, D.H., Ma, X.R., Li, P.Z., Zhai, W.J., Zhou, Z.Q., Wang, P*. Pectin reduces environmental pollutant-induced obesity in mice through regulating gut microbiota: A case study of p,p’-DDE. Environment International, 2019, 130, 104861.

10. Liang, Y.R.1, Zhan, J.1, Liu, D.H., Luo, M., Han, J.J., Liu, X.K., Liu, C., Cheng, Z., Zhou, Z.Q., Wang, P*. Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota. Microbiome, 2019, 7, 19.(共同一作)

11. Zhan, J., Liang, Y.R., Liu, D.H., Ma, X.R., Li, P.Z., Liu, C., Liu, X.K., Wang, P*, Zhou, Z.Q*. Antibiotics may increase triazine herbicide exposure risk via disturbing gut microbiota. Microbiome, 2018, 6, 224.

12. Zhan, J.1, Liang, Y.R.1, Liu, D.H., Liu, C., Liu, H., Wang, P., Zhou, Z.Q*. Organochlorine pesticide acetofenate and its hydrolytic metabolite in rabbits: Enantioselective metabolism and cytotoxicity. Pesticide Biochemistry and Physiology, 2018, 145, 76-83.

13. Zhan, J., Li, J.D., Liu, D.H., Liu, C., Yang, G.G., Zhou, Z.Q., Wang, P*. A simple method for the determination of organochlorine pollutants and the enantiomers in oil seeds based on matrix solid-phase dispersion. Food Chemistry, 2016, 194, 319-324.

14. 詹菁, 刘倩*, 张雨竹, 郝放, 梁勇, 曲广波, 胡立刚, 周群芳, 江桂斌. 新型冠状病毒2019-nCOV的一些初步认识. 环境化学, 2020, 39(2), 283-291. (中文核心,E方知库年度最受关注论文)

15. 刘福东, 刘力, 任怡镁, 赵雯, 刘伟贤, 洪维鍊, 桑跃, 詹菁*. 副干酪乳杆菌ET-22对金黄地鼠口腔溃疡的预防作用及机制. 品科学技术学报, 2023, 41(4), 107-117. EI收录)

16. Hu, Y., Han, F., Wang, Y.X., Zhong, Y.X., Zhan, J., Liu, J.Y*. Trimester-specific hemodynamics of per- and polyfluoroalkyl substances and its relation to lipid profile in pregnant women. Journal of Hazardous Materials, 2023, 460, 132339.

17. Liang, Y.R., Liu, D.H., Li, Y., Hou, H.N., Li, P.X., Ma, X.R., Li, P.Z., Zhan, J., Wang, P*. Maternal polysorbate 80 exposure causes intestinal ILCs and CD4+ T cell developmental abnormalities in mouse offspring. Environmental Pollution, 2023, 336, 122392.

18. Liu, J.Y., Song, L.L. Zhan, J., Zhong, Y.X., Shi, Z.X*. Occurrence of legacy and alternative per- and polyfluoroalkyl substances in serum from high exposure population and their disrupting effects on serum lipids and thyroid function. Science of The Total Environment, 2023, 878, 162988.

19. Liu, X.K., Wang, P., Liang, Y.R., Zhan, J., Liu, D.H.*, Zhou, Z.Q. Enantioselective characteristics, bioaccumulation and toxicological effects of chlordane-related compounds in laying hens. Chemosphere, 2022, 300, 134486.

20. Liang, Y.R., Liu, D.H., Zhan, J., Luo, M., Han, J.J., Wang, P., Zhou, Z.Q*. New insight into the mechanism of POP-induced obesity: Evidence from DDE-altered microbiota. Chemosphere, 2020, 244, 125123.

21. Liu, X.K., Liu, C., Wang, P., Liang, Y.R., Zhan, J., Zhou, Z.Q., Liu, D.H*. Distribution, metabolism and metabolic disturbances of alpha-cypermethrin in embryo development, chick growth and adult hens. Environmental Pollution, 2019, 249, 390-397.

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