2021.04-至今，中国农业大学营养与健康系，教授；

2019.02- 2021.03: 美国约翰霍普金斯大学，助理研究员；

2014.04-2019.02:  美国约翰霍普金斯大学Thomas Clemens实验室，博士后；

2013.07-2014.03: 中国科学院上海生命科学研究院营养科学研究所，助理研究员；

2008.09-2013.07: 中国科学院上海生命科学研究院营养科学研究所，博士；

2004.09-2008.06  中国农业大学，学士

1，骨骼发育与骨质疏松的分子机制

2，骨骼疾病与内分泌系统的相互调控作用

3，骨髓间充质干细胞对骨骼丢失和损伤修复的调控机制

1，国家自然科学基金面上项目（82272566）“MARK3介导的细胞极性在骨骼形成及骨折修复中的作用与机制研究”（2023-2026） 主持

2，北京市科技新星 (2022-2024）主持

3，中国农业大学高层次引进人才启动基金（2021-2025） 主持

4，国家自然科学基金青年项目“下丘脑长型催乳素受体(PRLR-L)对机体胰岛素敏感性的调控作用及分子机制”(2015-2017)  主持

1.      Qian Zhang, Larry D. Mesner, Gina M. Calabrese, Naomi Dirckx, Zhu Li, Angela Verardo, Qian Yang, Robert J. Tower, Marie-Claude Faugere, Charles R. Farber, and Thomas L. Clemens. Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts. Journal of Clinical Investigation. 2021;131(7):e142580.

2.      Qian Zhang, Ryan C. Riddle, Qian Yang, Clifford R. Rosen, Denis C. Guttridge, Naomi Dirckx, Marie-Claude Faugere, Charles R. Farber, and Thomas L. Clemens. The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage. Proceedings of the National Academy of Sciences. 2019, 116(36): 17980-17989.

3.      Wenliang Yan, Meng Shen, Kainong Sun, Shiming Li, Jingyuan Miao, Jun Wang, Jiayang Xu, Pengcheng Wen* and Qian Zhang* (* corresponding author). Norisoboldine, a natural isoquinoline alkaloid, inhibits diaph-yseal fracture healing in mice by alleviating cartilage formation. Biomedicines 2023, 11(7):2031.

4.      Ziquan Lv, Kai Fu, and Qian Zhang* (* corresponding author). Advances of exosomes-based applications in diagnostic biomarkers for dental disease and dental regeneration. Colloids and Surfaces B-Biointerfaces. 2023, 229:113429.（封面文章）

5.      Qian Zhang. New Insights into Nutrients for Bone Health and Disease. Nutrients 2023, 15(12), 2648.

6.      Ziquan Lv, Wenbiao Shi and Qian Zhang* (* corresponding author). Role of Essential Amino Acids in Aging-induced Bone Loss. International Journal of Molecular Sciences. 2022, 23(19):11281.

7.      Lu Chen#, Qian Zhang#, (#co-first-author), Ziwei Yi, Yu Chen, Weihan Xiao, Dan Su and Wenbiao Shi. Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors. Foods. 2022, 11(19), 2946.

8.      Qian Zhang, Michele Doucet, Ryan E Tomlinson, Xiaobin Han, L Darryl Quarles, Michael T Collins and Thomas L Clemens. The hypoxia-inducible factor-1α activates ectopic production of fibroblast growth factor 23 in tumor-induced osteomalacia. Bone Research. 2016, 4:16011.

9.      Qian Zhang, Riddle RC and Clemens TL. Bone and the regulation of global energy balance. Journal of Internal Medicine. 2015, 277(6):681–689.

10.   Tingting Xia#, Qian Zhang # (#co-first-author),Xiao Y, Wang C, Yu J, Liu H, Liu B, Zhang Y, Chen S, Liu Y, Chen Y, and Guo F. CREB/TRH pathway in the central nervous system regulates energy expenditure in response to deprivation of an essential amino acid. International Journal of Obesity. 2015, 39:105-113.

11.   Qian Zhang, Bin Liu, Ying Cheng, Qingshu Meng, Tingting Xia, Lei Jiang, Shanghai Chen, Yong Liu and Feifan Guo. Leptin signaling is required for leucine deprivation-enhanced energy expenditure. Journal of Biological Chemistry. 2014, 289:1779-1787.

12.   Qian Zhang, Junjie Yu, Bin Liu, Ziquan Lv, Tingting Xia, Fei Xiao, Shanghai Chen, and Feifan Guo. Central Activating Transcription Factor 4 (ATF4) Regulates Hepatic Insulin Resistance in Mice via S6K1 Signaling and the Vagus Nerve. Diabetes. 2013, 62(7): 2230-2239.

13.   Ying Cheng#, Qian Zhang# (#co-first-author), Qingshu Meng, Tingting Xia, Zhiying Huang, Chunxia Wang, Bin Liu, Shanghai Chen, Fei Xiao, Ying Du, and Feifan Guo. Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system. Molecular Endocrinology. 2011, 25(9):1624-1635.

14.   Qian Zhang, Houkai Li, Feifan Guo. Amygdala, an important regulator for food intake. Frontiers in Biology. 2011, 6(1):82-85.

15.   Qian Zhang, Jian Li, Jiankang Cao, Yang Cui, Weibo Jiang. Effects of UV-C on post-harvest quality and disease resistance of Yali pear fruit. Journal of China Agricultural University. 2009, 14(2):70-74.

16.    Naomi Dirckx, Qian Zhang, Emily Y. Chu, Robert J. Tower, Zhu Li, Shenghao Guo, Shichen Yuan, Pratik A. Khare, Cissy Zhang, Angela Verardo, Lucy O. Alejandro, Angelina Park, Marie-Claude Faugere, Stephen L. Helfand, Martha J. Somerman, Ryan C. Riddle, Rafael de Cabo, Anne Le, Klaus Schmidt-Rohr, and Thomas L. Clemens. A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth. Proceedings of the National Academy of Sciences. 2022, 119 (45): e2212178119.

17.    Ya Wang, Yuanbing Yao, Qunhui Wei, Shichao Long, Yuqiao Chen, Jinru Xie, Rong Tan, Wei Jiang, Qian Zhang, Dongbo Wu, Shuai Xiao, Fengyi Wan & Kai Fu. TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex. Oncogene 42: 586–600 (2023)

18.   Robert J. Tower, Zhu Li, Yu-Hao Cheng, Xue-Wei Wang, Labchan Rajbhandari, Qian Zhang, Stefano Negri, Cedric R. Uytingco, Arun Venkatesan, Feng-Quan Zhou, Patrick Cahan, Aaron W. James, and Thomas L. Clemens. Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling. Proceedings of the National Academy of Sciences. 2021; 118 (42): e2103087118

19.   Ryan E. Tomlinson, Zhi Li, Qian Zhang, Brian C. Goh, Zhu Li, Daniel L.J. Thorek, Labchan Rajbhandari, Thomas M. Brushart, Liliana Minichiello, Fengquan Zhou, Arun Venkatesan, Thomas L. Clemens. NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone. Cell Reports. 2016, 16(10):p2723–2735.

20.   Junjie Yu, Fei Xiao, Yajie Guo, Jiali Deng, Bin Liu, Qian Zhang, Kai Li, Chunxia Wang, Shanghai Chen, Feifan Guo. Hepatic phosphoserine aminotransferase 1 regulates insulin sensitivity in mice via tribbles homolog 3. 2015, Diabetes 64 (5):1591-1602

21.   Julie L. Frey, Zhu Li, Jessica M. Ellis, Qian Zhang, Charles R. Farber, Susan Aja, Michael J. Wolfgang, Thomas L. Clemens and Ryan C. Riddle. Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast. Molecular and Cellular Biology. 2015, 35(11):1979–1991.

22.   Fei Xiao, Tingting Xia, Ziquan Lv, Qian Zhang, Yuzhong Xiao, Junjie Yu, Hao Liu, Jiali Deng, Yajie Guo, Chunxia Wang, Kai Li, Bin Liu, Shanghai Chen and Feifan Guo. Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve. Diabetologia. 2014, 57(10):2136–2144.

23.   Hao Liu, Junjie Yu, Tingting Xia, Yuzhong Xiao, Qian Zhang, Bin Liu, Yajie Guo, Jiali Deng, Yalan Deng, Shanghai Chen, Aniko Naray-Fejes-Toth, Geza Fejes-Toth, Feifan Guo. Hepatic serum-and glucocorticoid-regulated protein kinase 1 (SGK1) regulates insulin sensitivity in mice via extracellular-signal-regulated kinase 1/2 (ERK1/2). Biochemical Journal, 2014, 464(2):281-289.

24.   Junjie Yu, Fei Xiao, Qian Zhang, Bin Liu, Yajie Guo, Ziquan Lv, Tingting Xia, Shanghai Chen, Kai Li, Ying Du and Feifan Guo. PRLR regulates hepatic insulin sensitivity in mice via STAT5. Diabetes. 2013, 62:3103-3113.

25.   Tingting Xia, Ying Cheng, Qian Zhang, Fei Xiao, Bin Liu, Shanghai Chen, Feifan Guo. S6K1 in the CNS regulates energy expenditure via MC4R/CRH pathways in response to deprivation of an essential amino acid. Diabetes.2012, 61(10):2461-71.

26.   Ying Du, Qingshu Meng, Qian Zhang, Feifan Guo. Isoleucine or valine deprivation stimulates fat loss via increasing energy expenditure and regulating lipid metabolism in WAT. Amino Acids. 2012, 43(2):725-734.

27.   Chunxia Wang, Houkai Li, Qingshu Meng, Ying Du, Fei Xiao, Qian Zhang, Junjie Yu, Kai Li, Shanghai Chen, Zhiying Huang, Bin Liu and Feifan Guo. ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expression. Journal of Cellular and Molecular Medicine 2014, 18(1):80-90.

28.   Jian Li, Qian Zhang, Yang Cui, Jiaqi Yan, Jiankang Cao, Yumei Zhao, and Weibo Jiang. Use of UV-C Treatment to Inhibit the Microbial Growth and Maintain the Quality of Yali Pear. Journal of Food Science. 2010, 75(7): M503-M507.