2022.10-至今：中国农业大学，优秀人才引进，副教授

2019.01-2022.09：中国科学院生物物理研究所，副研究员

2015.05-2018.12：中国科学院生物物理研究所，助理研究员

2009.09-2015.01：中国农业大学，动物生理学，理学博士

2005.09-2009.06：河北师范大学，生物科学，理学学士

精准营养与免疫健康

1. 中国农业大学2115“人才培育发展支持计划”青年新星A类，2024.01-2027.12，主持

2. 国家自然科学基金面上项目，2025.01-2028.12，主持

3. 国家自然科学基金面上项目，2020.01-2023.12，主持

4. 国家自然科学基金青年科学基金，2017.01-2019.12，主持

5. 国家重点研发计划课题，2023.12-2027.12，主持

6. 北京市自然科学基金面上项目，2018.01-2020.12，主持

7. 河南省重大科技专项课题，2024.06-2026.05，主持

8. 国家乳业技术创新中心省部级项目，2023.09-2025.12, 主持

9. 国家乳业技术创新中心课题，2023.12-2024.12, 主持

10. 中国农业大学基础研究与前沿创新专项，2024.01-2027.12，主持

1.Zhang WB^#, Chen C^#, Wang R^#, Li YX^#, Zhu YH, Sun JZ, Luo YT, Luo JJ, Zhao L, Sun YN, Guo HY, Zhang H, Fang B, Hu Y, Liu R, Wang XY, Guo JY, Liu P, An P, Wang PJ^*, Chen J^*, Ren FZ^*. Fe²⁺ Triggers Endocytosis of Carrier Protein in Mammalian Cells. Advanced Healthcare Materials. 2025 May 27:e2502090

2.Liu XX^#, Huang Y^#, Li YX^#, Chen J^#, Wang XF^#, Wang XB, Zhao L, Luo YT, An P, Zhang LW, Zhang CY, Bian WJ, Lei XG, Gao X, Liu YH, Hao YL, Guo HY, Zhang XX, Wang PJ, Wang R, Zhang H, Fang B, Hui Y, Zhang XL, Wang LJ, Qiu QL, Zhang YC, Qi JY, Yang ST^*, Yin YL^*, Ren FZ^*, Wang XY^*. Probiotics Restore Enteric HDL3 Secretion and Improve Prognosis in Patients with End-Stage Renal Disease. iMeta. 2025 (In press)

3.Wang J^#, Ren YM^#, Chen J^#, Chen SB^#, Li XX^#, Wang XF, Li LJ, Zhao L, Li YX, Zhang Q, Xiong W, Guo HY, Zhang H, Zhang XX, Wang FQ, Hao YL, He JJ, Fang B, Guo J, Ge SY, Ren FZ, Zhang LW^*, Luo J^*, Wang R^*, Yin YL^*. Bifidobacterium animalis subsp. lactis A6 alleviates depression by rebalancing tryptophan metabolism. Science Bulletin. 2025 Apr 21:S2095-9273(25)00400-1

4.Xie XM, Chen XX, Wang CF, Sun LJ, Yu WR, Lv Z, Tian S, Yao XH, Wang FC, Ding DQ^*, Chen J^*, Liu JL^*. PARN maintains RNA stability to regulate insulin maturation and GSIS in pancreatic  cells. Advanced Science. 2024 https://doi.org/10.1002/advs.202407774

5.Liu P^#, Jannatul Refeya^#, Chen J^#, Hou LH^#, Gao MJ, Wang PJ, Jin DK, Chen H, Liu R, Wang R, Jia LR, Li YX, Fang B, Sun YN, Zhang YX, Ren FZ, Lin WL. Programmable Chemical Evolution with Natural/non-natural Building Blocks. Angewandte Chemie International Edition. 2024 https://doi.org/10.1002/anie.202409746 (Cover story)

6.Zhang YG, Lei YM, Dong YB, Chen SW, Sun SY, Zhou FE, Zhao ZW, Chen BN, Wei L^*, Chen J^*, Meng ZJ^*. Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases. Pharmacology & Therapeutics. 2024 Jan 253, 108576

7.Chen Y^#, Sun SY^#, Lu CX^#, Li YX^#, Fang B^#, Tang XF, Li XP, Yu WR, Lei YM, Sun LJ, Zhang M, Sun JZ, Liu P, Luo YT, Zhao XW, Zhan J, Liu LB, Liu R, Huang JQ, Yi ZW, Yu YF, Xiao WH, Ding Z, Li L, Su D, Ren FZ^*, Cao CC^*, Wang R^*, Shi WB^*, Chen J^*. The RNA binding protein Bcas2 is required for antibody class switch in activated-B cells. Exploration. 2025 https://doi.org/10.1002/EXP.70015

8.Han TS, Wei W, Jiang WB, Geng YD, Liu ZJ, Yang RM, Jin CR, Lei YT, Sun XY, Xu JX, Zhou N, Chen J^*, Sun CH^*. The Future landscape and framework of precision nutrition. Engineering. 2024. 42: 15-25

9.Sun SY, Fang B, Wang R, Ren FZ, Chen J^*. ERV: a promising new target for lung adenocarcinoma treatment. Science Bulletin. 2023 Oct 15;68(19):2135-2138

10.Chen J, Cai ZK, Bai MZ, Yu XH, Zhang C, Cao CC, Hu XH, Wang L, Su RB, Wang D, Wang L, Yao YP, Ye R, Hou BD, Yu Y, Yu SY, Li JS, Xue YC^*. The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. Cell Research. 2018, Aug 24; 28:981-995. (Cover story and Research Highlight) 

11.Wang R^#, Sun SY^#, Zhang Q^#, Wu GL, Ren FZ^*, Chen J^*. Maternal Milk Orchestrates the Development of Infant Gut Microbiota: Implications for Health and Future Research Directions. Research. 2024 DOI: 10.34133/research.0558

12.Wang R^#, Yu YF^#, Yu WR^#, Sun SY, Lei YM, Li YX, Lu CX, Zhai JN, Bai FR, Ren FZ, Huang JQ^*, Chen J^*. Roles of Probiotics, Prebiotics, and Postbiotics in B-Cell-Mediated Immune Regulation. The Journal of Nutrition. 2024 Nov 17: S0022-3166(24)01178-7 (Cover story)

13.Chen J^#, Yu YF^#, Sun SY^#, Yu WR, Lei YM, Lu CX, Zhai JN, Bai FR, Ren FZ^*, Wang R^*. Probiotics and Prebiotics: Meeting Dietary Requirements for Optimal Health and Planetary Sustainability. The Journal of Nutrition. 2025 Mar 22: S0022-3166(25)00179-8

14.Zhao WT^#, Chen J^#, Xia Y^#, Wei ZX, Wan ST, Guo HY, Hao YL, Jiang WJ, Zhang HJ, Ren FZ^*, An P^*, Luo YT^*, Luo JJ^*. Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets. Science Bulletin. 2024 Jul 4:S2095-9273(24)00462-6

15.Sun LJ^#, Chen J^#, Ye R, Lv Z, Chen XX, Xie XM, Li YH, Wang CF, Lv PB, Yan L, Tian S, Yao XH, Chen C, Cui S, Liu JL^*. SRSF1 is crucial for male meiosis through alternative splicing during homologous pairing and synapsis in mice. Science Bulletin. 2023 Jun 15;68(11):1100-1104 (Cover story and Research Highlight)

16.Sun LJ, Lv Z, Chen XX, Ye R, Tian S, Wang CF, Xie XM, Yan L, Yao XH, Shao YJ, Cui S, Chen J^*, Liu JL^*. Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice. Elife. 2024 Jan 25:12:RP89316. doi: 10.7554/eLife.89316.

17.Sun LJ, Ye R, Cao CC, Lv Z, Wang CF, Xie XM, Chen XX, Yao XH, Tian S, Yan L, Shao YJ, Cui S, Chen C, Xue YC^*, Li L^*, Chen J^*, Liu JL^*. BCAS2 and hnRNPH1 orchestrate alternative splicing for DNA double-strand break repair and synapsis in meiotic prophase I. Cellular and Molecular Life Sciences. 2024 Nov 9;81(1):449. doi: 10.1007/s00018-024-05479-7

18.Chen J, Xue YC^*. Emerging roles of non-coding RNAs in epigenetic regulation. Science China Life Sciences. 2016, 59(3):227-235.

19.Chen J, Fu R, Cui Y, Pan JR, Li YS, Zhang XX, Evans Sylvia M, Cui S, Liu JL^*. LIM-homeodomain transcription factor Isl-1 mediates kisspeptin’s effect on insulin secretion in mice. Molecular Endocrinology. 2014 Aug; 28(8):1276-90.

20.Chen J, Fu R, Cui Y, Li YS, Pan JR, Liu JL, Luo HS, Yin JD, Li DF^*, Cui S^*. LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice. Journal of Biological Chemistry. 2013 Apr 26;288(17):12395-405.

21.Zhao HL, Cai ZK, Rao J, Wu D, Ji L, Ye R, Wang D, Chen J, Cao CC, Hu NJ, Shu T, Zhu P, Wang JW, Zhou X, Xue YC. SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis. Molecular cell. 2024 Feb 1;84(3):490-505.e9

22.Liang L, Cao CC, Ji L, Cai ZK, Wang D, Ye R, Chen J, Yu XH, Zhou J, Bai ZB, Wang RY, Yang XG, Zhu P, Xue YC^*. Complementary Alu sequences mediate enhancer-promoter selectivity. Nature. 2023 Jul;619(7971):868-875

23.Cai ZK, Cao CC, Ji L, Ye R, Wang D, Xia C, Wang S, Du ZC, Hu NJ, Yu XH, Chen J, Wang L,Yang XG, He SM, Xue YC^*. RIC-seq for global in situ profiling of RNA - RNA spatial interactions. Nature. 2020, 582(7812):432-437.

24.Cao CC, Cai ZK, Xiao X, Rao J, Chen J, Hu NJ, Yang MN, Xing XR, Wang YL, Li MM, Zhou B, Wang XX, Wang JW^*, Xue YC^*. The architecture of the SARS-CoV-2 RNA genome inside virion. Nature communications. 2021, 12(1):3917.

学术兼职：

中原食品实验室 岗位科学家

中国乳制品工业协会科学技术专业委员会  专家

国际乳品联合会中国国家委员会  专家

中国营养学会会员

中国营养学会杂志IJVNR青年编委

The innovation 青年编委

Exploration 青年编委

Journal of Nutrition, Health and Aging 编委

专利：

共授权专利25项，其中第一发明人授权专利5项

奖项：

2025中国农业大学校级优秀学位论文 指导教师

2024年国际基因工程机器大赛iGEM银奖 指导教师

2024年 第十三届大北农科技奖一等奖（第九完成人）

国际乳品联合会中国国家委员会  乳业优秀青年科技工作者

中国乳制品工业协会  技术发明奖  一等奖 （第一完成人）

中国乳制品工业协会  技术进步奖  二等奖 （第一完成人）

中国商业联合会  科学技术奖  特等奖 （排名6/11）

中国商业联合会  科学技术奖  一等奖 （排名5/11）

中国检验检测学会  科学技术奖  特等奖 （排名10/19）