2005-2009 武汉大学生命科学学院，本科

2009-2014 中国科学院营养科学研究所/华东理工大学， 硕博连读

2014-2016 浙江大学转化医学研究院，助理研究员

2016-2020 中国农业大学食品营养与人类健康高精尖创新中心，岗位科学家

2020-2022 中国农业大学理学院，博士后

2022-今 中国农业大学营养与健康系，副教授

主要研究方向为微量营养素稳态与代谢性疾病。通过多种手段探究微量营养素的稳态调控机制及其失衡对常见慢病的影响，开发具有针对性的营养干预策略。

国家自然基金面上项目，项目负责人，2026.1 - 2029.12

国家自然基金面上项目，项目负责人，2024.1 - 2027.12

国家自然基金青年科学基金，项目负责人，2016.1 - 2018.12

国家重点研发计划，子课题任务负责人，2023.12 - 2027.12

1.         Zhao W,^# Wang P,^#/* Liu Z,^# Zhang D, Xia Y, Xu T, Wang F, Cui M, Zhang X, Zhou S, Wei Z, Ma M, Wan S, Qi J, Zhang Z, Chen J, Liu L, Zhu Y, Luo J*, Luo Y*, An P*. The endothelial mTORC2-Foxo1 axis serves as an iron-responsive sensor governing systemic iron homeostasis. Blood, 2025;146(14):1722–36 (封面论文, * Corresponding author). Editorial: Pantopoulos K. Foxo1 unlocks the liver endothelial code to iron sensing. Blood 2025;146(14):1639–41.

2.         Wan S, Qi J, Xia Y, Fan C, Xu T, Zhang X, Shi J, Wang C, Cheng Y, Zhang D, Liu R, Zhu Y, Cao C, Jin D, An P, * Luo Y, * Luo J*. Cardiac Slc25a49-Mediated Energy Reprogramming Governs Doxorubicin-Induced Cardiomyopathy through the G6P–AP-1–Sln Axis. Advanced Science, 2025;12(26):2502163.

3.         Xu T,^# Zhang X,^# Zhao W, Shi J, Wan S, Zhang Y, Hao Y, Sun M, He J, Jiang L, Wang H, Gao H*, Luo J*, Luo Y*, An P*. Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis. Blood, 2024; 144, 1314–1328 (封面论文, * Corresponding author). Editorial: Yien, Y.Y. What does the FOX(O) say? High iron: hepcidin! Blood 2024; 144, 1243–1245.

4.         Zhao W, ^# Chen J, ^# Xia Y, ^# Wei Z, Wan S, Guo H, Hao Y, Jiang W, Zhang H, Ren F*, An P*, Luo Y*, Luo J*. Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets. Science Bulletin, 2025;70(2):167–71 (* Corresponding author).

5.         An P,^# Wan S,^# Wang L, Xu T, Xu T, Wang Y, Liu J, Li K, Wang X,* He J,* Liu S*. Modifiers of the Effects of Vitamin D Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Engineering, 2024;42;99-107 (# Co-first author).

6.         Luo Y, ^# Luo J, ^# An P, ^# Zhao Y,^# Zhao W,^# Fang Z, Xia Y, Zhu L, Xu T, Zhang Xu, Zhou S, Yang M, Li J, Zhu J, Liu Y, Li H, Gong M, Liu Y, Han J, Guo H,^# Zhang H,^* Jiang W,^* Ren F^*. The AP-1 complex governs a vascular degenerative transcriptional program in smooth muscle cells to trigger aortic dissection and rupture. European Heart Journal 2023;45(4):287–305 (# Co-first author). Editorial: Miteva, K. On target inhibition of vascular smooth muscle cell phenotypic transition underpins TNF–OXPHOS–AP-1 as a promising avenue for anti-remodelling interventions in aortic dissection and rupture. European Heart Journal 2023;45(4):306–8.

7.         Wang X, ^# Ji Y, ^# Qi J, Zhou S, Wan S, Fan C, Gu Z, An P,* Luo Y,* Luo J *. Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells. Cell Death & Disease, 2023;14(8):508 (* Corresponding author).

8.         An P,^# Wan S,^# Luo Y, Luo J, Zhang X, Zhou S, Xu T, He J, Mechanick JI, Wu WC, Ren F,* Liu S*. Micronutrient Supplementation to Reduce Cardiovascular Risk. Journal of the American College of Cardiology 2022;80(24):2269–85 (# Co-first author). Editorial: Gormaz JG, Carrasco R. Antioxidant Supplementation in Cardiovascular Prevention: New Challenges in the Face of New Evidence. J Am Coll Cardiol 2022;80(24):2286–8.