2026.06-至今：中国农业大学，营养与健康系，副教授（优秀人才引进）

2022.07-2026.05：中国农业大学，营养与健康系，博士后/副研究员（资格）

2018.09-2022.06：中国农业大学，动物科学技术学院，博士

2015.09-2018.06：山东农业大学，动物科技学院，硕士

2011.09-2015.06：山东农业大学，动物科技学院，本科

1、动物营养与黏膜免疫、抗病营养学

2、消化道微生物调控宿主防御功能的免疫学和营养表观遗传学机制

3、幼龄动物肠道抗应激能力的营养调控机制研究和产品开发

4、动物营养与人类健康

1、国家自然科学基金青年基金，藏猪源丁酸梭菌增强断奶仔猪结肠巨噬细胞溶菌酶表达的分子机制，在研，主持

2、国家资助博士后研究人员计划B档，结题，主持

3、中国博士后基金面上项目，结题，主持

科研论文：

1. Wu J, Guo P, Wang M, Men Z, Lin Z, Wang J, Zhang S, Zhou M, Zhao J, Liu H, Ma X. Butyrate-producing commensal bacteria confers colon immune defense function via enhancing H4K31 Crotonylation of macrophages. Microbiome. 2025;14(1):8. doi: 10.1186/s40168-025-02234-3.

2. Wu J#, Zhang M#, Zhang H#, Sheng M, Sun J, Gao H, Chen L, Li Z, Tian Q, Zhu L, Fang B. PMN-MDSC: The culprit behind aging-related immunosenescence and increased susceptibility to Clostridioides difficile infection. Engineering. 2024;42:59-73. doi: 10.1016/j.eng.2024.06.014.

3. Tang X, Wu J#, Hu Z, Tang M, Chen F, Yao Y, Chen G, Xiong X, Zhou B, Gao YZ, Jiang Q, Zhang Chen, Wang L, Li Y, Wang X, Xiong X, He L, Wang L, Blachier F, Wang R, Kim SW, Yin Y. Tryptophan metabolism in inter-organ communication and its potential applications for disease prevention and control. The Innovation Life. 2025;3:100177. doi: 10.59717/j.xinn-life.2026.100177.

4. Wang M#, Xu X#, Sheng M, Zhang M, Zhao Z, Guo M, Fang B*, Wu J*. Tannic acid protects against colonitis by regulating the IL17–NFκB and microbiota–methylation pathways. Int J Biol Macromol. 2024;274(Pt 1):133334. doi: 10.1016/j.ijbiomac.2024.133334.

5. Wu J, Lin Z, Wang J, Liu C, Zhao J, Liu H, Ma X. Limosilactobacillus reuteri SLZX19-12 enhances intestinal barrier function and reduces inflammatory response to alleviate weaning stress of piglets. J Funct Foods. 2024;114(7):106094. doi: 10.1016/j.jff.2024.106094.

6. Wu J, Wang J, Lin Z, Liu C, Zhang Y, Zhang S, Zhou M, Zhao J, Liu H, Ma X. Clostridium butyricum alleviates weaned stress of piglets by improving intestinal immune function and gut microbiota. Food Chem. 2023;405(Pt B):135014. doi: 10.1016/j.foodchem.2022.135014.

7. Wang M#, Wu J#, Jiao H, Oluwabiyi C, Li H, Zhao J, Zhou Y, Wang X, Lin H. Enterocyte synthesizes and secrets uric acid as antioxidant to protect against oxidative stress via the involvement of Nrf pathway. Free Radic Biol Med. 2022;179:95-108. doi: 10.1016/j.freeradbiomed.2021.12.307.

8. Wu J, Zhao Y, Wang X, Kong L, Johnston LJ, Lu L, Ma X. Dietary nutrients shape gut microbes and intestinal mucosa via epigenetic modifications. Crit Rev Food Sci. 2022;62(3):783-797. doi: 10.1080/10408398.2020.1828813.

9. Wu J, Lin Z, Wang X, Zhao Y, Zhao J, Liu H, Johnston LJ, Lu L, Ma X. Limosilactobacillus reuteri SLZX19-12 protects colon from infection by enhancing stability of gut microbiota and barrier integrity and reducing inflammation. Microbiol Spectr. 2022;10(3):e0212421. doi: 10.1128/spectrum.02124-21.

10. Wu J, Ma N, Johnston LJ, Ma X. Dietary nutrients mediate intestinal host defense peptide expression. Adv Nutr. 2020;11(1):92-102. doi: 10.1093/advances/nmz057.

11. Tang D#, Wu J#, Jiao H, Wang X, Zhao J, Lin H. The development of antioxidant system in the intestinal tract of broiler chickens. Poult Sci. 2019;98(2):664-678. doi: 10.3382/ps/pey415.

12. Zhao Z#, Wu J#, Sun Z, Fan J, Liu F, Zhao W, Liu W, Zhang M, Hung W. Postbiotics derived from L. paracasei ET-22 inhibit the formation of S. mutans biofilms and bioactive substances: an analysis. Molecules. 2023;28(3):1236. doi: 10.3390/molecules28031236.

13. Guo M#, Wu J#, Hung W, Sun Z, Zhao W, Lan H, Zhao Z, Wuri G, Fang B, Zhao L, Zhang M. Lactobacillus paracasei ET-22 suppresses dental caries by regulating microbiota of dental plaques and inhibiting biofilm formation. Nutrients. 2023;15(15):3316. doi: 10.3390/nu15153316.

专著：

1.《食品产业高质量发展战略研究》，编委，2024

专利：

1. 一种丁酸梭菌SLZX19-05及其应用，专利号：ZL202111000096.8

2. 一种罗伊氏乳杆菌及其应用，专利号：ZL202011357177.9

3. 一种噬淀粉乳杆菌及其应用，专利号：ZL202110915199.0

4. 一种H4K31巴豆酰化修饰的抗原表位肽、多克隆抗体及其制备方法和用途

5. 一种基于Crispr基因编辑技术构建哺乳动物白细胞减少症模型的方法

科研奖励：

1. 2025年获得中国商业联合会科技进步特等奖（第四完成人）

2. 2025年获得中国·山东博士后创新创业大赛金奖（2/3，山东省人力资源和社会保障厅）

3. 2024年获得中国·山东博士后创新创业大赛银奖（1/3，山东省人力资源和社会保障厅）

4. 2024年获得博士后科研业绩评估考核一档资助