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师资力量

  • 姓  名:刘礼兵
  • 性  别:男
  • 职  称:教授
  • 所在系别:营养与健康系
  • 办公地点:中国农业大学建大校区1号楼
  • 电子邮箱:liulibing@cau.edu.cn
个人简历

2021.12-至今,中国农业大学营养与健康系, 教授

2018-2021,中国科学院化学研究所, 研究员

2007-2018,中国科学院化学研究所, 博士后,助理研究员,副研究员

2003-2007,军事医学科学院,博士

2000-2003,中国农业大学生物学院,硕士

1996-2000,中国农业大学生物学院,学士


参与奖项:中国科学院卢嘉锡青年人才奖,北京市科学技术一等奖,中科院青年创新促进会优秀会员


研究方向

化学与生物学交叉研究

1. 生物复合共轭聚合物荧光新材料

2. 分子探针与疾病早期诊断

3. 分子功能材料与营养健康

4. 食品安全与阻控技术

更多信息见:http://faculty.cau.edu.cn/yyyjkx/llb/list.htm


课题项目

1、 中国农业大学杰出人才启动项目,2021.12-2027.3,主持

2、 国家自然科学基金面上项目, 共轭聚合物纳米粒子调控巨噬细胞极化及其抗肿瘤研究,2021/12-2024/12,主持

3、 国家重点研发计划,基于共轭分子组装体的病原菌快速检测,2019/8-2022/7,主持

4、 国家自然科学基金面上项目,共轭聚合物光热性能及其基因调控研究,2018/01-2021/12,主持

5、 中国科学院A类战略性先导科技专项,功能化及个性化的生物3D打印团队任务3:生物材料定制,2017/12-2022/11,参加

6、 国家自然科学基金重点项目,多功能共轭聚合物复合材料的设计,合成及其抗肿瘤与抗菌活性研究,2016/01-2020/12,参加

7、 中国科学院战略性先导科技专项(B类),高性能柔性有机场效应晶体管及其阵列的研究,2014/7-2019/06,参加

8、 国家自然科学基金重大研究计划集成项目,多级可控组装模拟生物体系的功能,2016/01-2018/12,参加

9、 国家自然科学基金面上项目,共轭聚合物与细菌的相互作用及群体感应与耐药性研究,2015/01-2018/12,主持

10、 北京市科委,基于新型荧光材料的肺癌检测技术研究,2013/04-2015/03,参加

11、 中国科学院化学研究所“一三五”规划项目,结直肠肿瘤药物敏感性检测技术研究,2013/10-2014/9,主持

12、 国家自然科学基金重点项目,基于有机功能材料的肿瘤标志物分子识别与细胞成像研究,2011/01-2014/12,参加

13、 国家重点基础研究发展计划(973计划),分子电子学的基础与应用探索研究,2011/01-2015/12,参加

14、 国家自然科学基金青年科学基金,新型共轭聚合物与生物大分子的自组装及其药物控释监测研究,2011/01-2013/12,主持

15、 国家重点基础研究发展计划(973计划),多模态智能化纳米分子影像探针及其在结直肠癌诊断与研究中的应用,2011/01-2015/12,参加

16、 中国科学院分子科学中心创新项目,共轭聚合物与生物大分子的自组装及其药物可监控释放研究,2009/12-2010/12,主持


论文著作

出版专著:《功能有机共轭分子体系的生物应用基础》、《纳米生物材料》、《分子仿生》、《DNA纳米技术》


1.       Conjugated polymer materials for detection and discrimination of pathogenic microorganisms: Guarantee of biosafety, Fengyan Wang, Min Ma, Huanzhang Cao, Xingxuan Chai, Ming Huang, Libing Liu*, Biosaf. Health. 2022, 4, 79-86.

2.       A hybrid nano-assembly with synergistically promoting photothermal and catalytic radical activity for antibacterial therapy, Yunxia Wang, Chuangxin Zhang, Hui Zhang, Liheng Feng*, Libing Liu*, Chin. Chem. Lett. 2022, 33, 4605-4609.

3.       共轭聚合物生物电子体系研究进展, 刘礼兵, 周鑫, 白昊天, 黄一鸣, 吕凤婷, 王树, 中国科学: 化学, 2022, 52, 241-249. (庆祝朱道本院士80华诞专刊)

4.       Nan Dai, Hao Zhao, Wen Yu, Fengting Lv, Libing Liu*, Shu Wang*, Oligo(p-Phenylenevinylene)- Rhodium Complex as Intracellular Catalyst for Enhancing Biosynthesis of Polyhydroxybutyrate Biomaterials, Sci. China Chem. 2021,1,143-150.

5.       Polymer nanoparticles regulate macrophage repolarization for antitumor treatment, Xuancheng Fu, Jiamu Yu, Anran Yuan, Libing Liu*, Hao Zhao, Yiming Huang, Song Shen, Fengting Lv and Shu Wang, Chem. Commun., 2021, 57, 6919 

6.       Oral delivery of antioxidant enzymes for effective treatment of inflammatory disease, Zhiying Zeng, Xiao He, Changying Li, Shan Lin, Hui Chen*, Libing Liu*, Xuli Feng*, Biomaterials, 2021, 271 120753.

7.       Clickable amino acid derivative tuned self-assembly of antigen and adjuvant for cancer immunotherapy, Xiao He, Lan Yang, Hang Su, Shan Lin, Dongmei Qi, Hui Chen*, Yunfei Qu*, Libing Liu*, Xuli Feng*, J. Control. Release, 2021, 337, 306-316.

8.       Yuqi Liu, Liuyang Tian, Yang Li, Yanyan Chen, Yundai Chen*, Libing Liu*, Shu Wang, Photoactive Oligo(p-phenylene vinylene) Material for Functional Regulation of Induced Pluripotent Stem Cells, ACS Appl. Mater. Interfaces, 2020, 12, 3438-3444.

9.       Syeda Sadia Khatoon, Yanyan Chen, Hao Zhao, Fengting Lv, Libing Liu*, Shu Wang*,In situ self-assembly of conjugated polyelectrolytes for cancer targeted imaging and photodynamic therapy, Biomater. Sci. 2020, 8, 2156-2163.

10.    Han Sun, Jing Liu, Shengliang Li, Lingyun Zhou, Jianwu Wang, Libing Liu*, Fengting Lv, Qi Gu*, Baoyang Hu, Yuguo Ma* and Shu Wang*, Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly, Angew. Chem. Int. Ed. 2019, 131, 5988-5993.

11.    Linye Jiang, Haotian Bai, Libing Liu*, Fengting Lv, Xueqin Ren* and Shu Wang*, Luminescent, Oxygen-Supplying, Hemoglobin-Linked Conjugated Polymer Nanoparticles for Photodynamic Therapy, Angew. Chem. Int. Ed. 2019, 58, 10660-10665. 

12.    Han Sun, Fengting Lv, Libing Liu*, Shu Wang*, Reactive Conjugated Polymers for Modulation of Islet Amyloid Polypeptide Assembly, ACS Appl. Mater. Interfaces, 2019, 11, 22973-22978.

13.    Xuancheng Fu, Haotian Bai, Ruilian Qi, Hao Zhao, Ke Peng, Fengting Lv, Libing Liu*, Shu Wang*, Optically-controlled supramolecular self-assembly of an antibiotic for antibacterial regulation, Chem. Commun., 2019, 55, 14466–14469.

14.    Yunxia Wang, Shengliang Li*, Pengbo Zhang, Haotian Bai, Liheng Feng, Fengting Lv, Libing Liu*, Shu Wang*, Photothermal-Responsive Conjugated Polymer Nanoparticles for Remote Control of Gene Expression in Living Cells, Adv. Mater. 2018, 30, 1705418.

15.    Thangaraj Senthilkumar, Lingyun Zhou, Libing Liu*, Fengting Lv, and Shu Wang*, Conjugated Polymer Nanoparticles Appending Photo-Responsive Units for Controlled Drug Delivery, Release and Imaging, Angew. Chem. Int. Ed. 2018, 57, 13114-13119.

16.    Yanyan Chen, Lingyun Zhou, Jianwu Wang Xiaoyan Liu, Huan Lu, Libing Liu*, Fengting Lv, and Shu Wang*, Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells, ACS Appl. Mater. Interfaces 2018, 10, 27555–27561.

17.    Meng Li, Ping He, Shengliang Li, Xiaoyu Wang, Libing Liu*, Fengting Lv, Shu Wang*, Oligo(p-phenylenevinylene) Derivative-Incorporated and Enzyme-Responsive Hybrid Hydrogel for Tumor Cell-Specific Imaging and Activatable Photodynamic Therapy, ACS Biomater. Sci. Eng. 2018, 4, 2037-2045.

18.    Ping He, Fengting Lv, Libing Liu*, Shu Wang*, Synthesis of amphiphilic poly(fluorene) derivatives for selective imaging of Staphylococcus aureus, Sci. Bul., 2018, 63, 900-906.

19.    Endong Zhang, Libing Liu*, Fengting Lv, and Shu Wang*, Design and Synthesis of Reactive Perylene Tetracarboxylic Diimide Derivatives for Rapid Cell Imaging, ACS Omega, 2018, 3, 8691–8696.

20.    Yunxia Wang, Shengliang Li, Libing Liu*, Fengting Lv and Shu Wang*, Conjugated Polymer Nanoparticles Augment Photosynthesis of Chloroplasts, Angew. Chem. Int. Ed. 2017, 56, 5308-5311.

21.    Rong Hu, Shengliang Li, Huan Lu, Libing Liu*, Fengting Lv, Shu Wang*, Supramolecular conjugated polymer materials for organelle imaging in living cells, Mater. Chem. Frontiers 2017, 1, 1768-1772.

22.    Pengbo Zhang, Shengliang Li, Hui Chen, Xiaoyu Wang, Libing Liu*, Fengting Lv, Shu Wang*, Biofilm inhibition and elimination regulated by cationic conjugated polymers, ACS Appl. Mater. Interfaces 2017, 9, 16933-16938.

23.    Bing Wang, Chenyao Nie, Libing Liu*, Fengting Lv, Shu Wang*, Selective biocompatibility and responsive imaging property of cationic conjugated polyelectrolyte to cancer cells Chin. Chem. Lett. 2017, 28, 1975-1978.

24.    Meng Li, Shengliang Li, Hui Chen, Rong Hu, Libing Liu*, Fengting Lv, Shu Wang*, Preparation of Conjugated Polymer Grafted with H2O2-Sensitive Prodrug for Cell Imaging and Tumor Cell Killing, ACS Appl. Mater. Interfaces, 2016, 8(1), 42-46.

25.    Rong Hu, Shengliang Li, HaoTian Bai, YunXia Wang, Libing Liu*, Fengting Lv, Shu Wang*, Regulation of oxidative stress inside living cells through polythiophene derivatives, Chin. Chem. Lett. 2016, 4, 545.

26.    Pengbo Zhang, Huan Lu, Hui Chen, Jiangyan Zhang, Libing Liu*, Fengting Lv, Shu Wang*, Cationic conjugated polymers-induced quorum sensing of bacteria cells, Anal. Chem. 2016, 6, 2985-2988.

27.    Yaokun Wang, Hui Chen, Meng Li, Rong Hu, Fengting Lv *, Libing Liu*, Shu Wang*, Synthesis of a new cationic non-conjugated polymer for discrimination of microbial pathogens, Polym. Chem-Uk, 2016, 44, 6699.


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