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师资力量

  • 姓  名:陈娟
  • 性  别:女
  • 职  称:副教授
  • 所在系别:营养与健康系
  • 办公地点:中国农业大学建大校区1号楼
  • 电子邮箱:chenjuan@cau.edu.cn
个人简历

2022.10-至今:中国农业大学,优秀人才引进,副教授

2019.01-2022.09:中国科学院生物物理研究所,副研究员

2015.05-2018.12:中国科学院生物物理研究所,助理研究员

2009.09-2015.01:中国农业大学,动物生理学,理学博士

2005.09-2009.06:河北师范大学,生物科学,理学学士

研究方向

食品精准营养与免疫健康

课题项目

1. 中国农业大学“人才培育发展支持计划”青年新星A类

2. 国家自然科学基金面上项目,2025-2028,主持

3. 国家重点研发计划课题,2023-2027,主持

4. 国家乳业技术创新中心省级项目,2023-2025, 主持

5. 国家乳业技术创新中心横向课题,2023-2024, 主持

6. 中国农业大学自主科研项目,2024-2024,主持

7. 中国农业大学基本科研业务费,2023-2023,主持

8. 国家自然科学基金面上项目,2020-2023,主持

9. 国家自然科学基金青年科学基金,2017-2019,主持

10.  北京市自然科学基金面上项目,2018-2020,主持

论文著作

1.Wang R#, Sun SY#, Zhang Q#, Wu GL, Ren FZ*, Chen J*. Maternal Milk Orchestrates the Development of Infant Gut Microbiota: Implications for Health and Future Research Directions. Research. 2024 (In press)

2.Xie XM, Chen XX, Wang CF, Sun LJ, Yu WR, Lv Z, Tian S, Yao XH, Wang FC, Ding DQ*, Chen J*, Liu JL*. PARN maintains RNA stability to regulate insulin maturation and GSIS in pancreatic b cells. Advanced Science.2024 https://doi.org/10.1002/advs.202407774

3. Liu P#, Jannatul Refeya#, Chen J#, Hou LH#, Gao MJ, Wang PJ, Jin DK, Chen H, Liu R,Wang R, Jia LR, Li YX, Fang B, Sun YN, Zhang YX, Ren FZ, Lin WL. Programmable Chemical Evolution with Natural/non-natural Building Blocks. Angewandte Chemie International Edition.2024 https://doi.org/10.1002/anie.202409746 (Cover story)

4. Zhao WT#, Chen J#, Xia Y#, Wei ZX, Wan ST, Guo HY, Hao YL, Jiang WJ, Zhang HJ, Ren FZ*, An P*, Luo YT*, Luo JJ*. Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets. Science Bulletin. 2024 Jul 4:S2095-9273(24)00462-6

5. Zhang YG, Lei YM, Dong YB, Chen SW, Sun SY, Zhou FE, Zhao ZW, Chen BN, Wei L*, Chen J*, Meng ZJ*. Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases. Pharmacology & Therapeutics. 2024 Jan 253, 108576

6. Han TS, Wei W, Jiang WB, Geng YD, Liu ZJ, Yang RM, Jin CR, Lei YT, Sun XY, Xu JX, Zhou N, Chen J*, Sun CH*. The Future landscape and framework of precision nutrition. Engineering. (2024) (In press)

7. Sun SY, Fang B, Wang R, Ren FZ, Chen J*. ERV: a promising new target for lung adenocarcinoma treatment. Science Bulletin. 2023 Oct 15;68(19):2135-2138

8. Sun LJ#, Chen J#, Ye R, Lv Z, Chen XX, Xie XM, Li YH, Wang CF, Lv PB, Yan L, Tian S, Yao XH, Chen C, Cui S, Liu JL*. SRSF1 is crucial for male meiosis through alternative splicing during homologous pairing and synapsis in mice. Science Bulletin. 2023 Jun 15;68(11):1100-1104 (Cover story and Research Highlight)

9. Chen J, Cai ZK, Bai MZ, Yu XH, Zhang C, Cao CC, Hu XH, Wang L, Su RB, Wang D, Wang L, Yao YP, Ye R, Hou BD, Yu Y, Yu SY, Li JS, Xue YC*. The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. Cell Research. 2018, Aug 24; 28:981-995. (Cover story and Research Highlight

10. Sun LJ, Lv Z, Chen XX, Ye R, Tian S, Wang CF, Xie XM, Yan L, Yao XH, Shao YJ, Cui S, Chen J*, Liu JL*. Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice. Elife. 2024 Jan 25:12:RP89316. doi: 10.7554/eLife.89316.

11.Sun LJ, Ye R, Cao CC, Lv Z, Wang CF, Xie XM, Chen XX, Yao XH, Tian S, Yan L, Shao YJ, Cui S, Chen C, Xue YC*, Li L*, Chen J*, Liu JL*. BCAS2 and hnRNPH1 orchestrate alternative splicing for DNA double-strand break repair and synapsis in meiotic prophase I. Cellular and Molecular Life Sciences. 2024 (In press)

12. Dong YB, Tang XL, Zhao WH, Liu P, Yu WR, Ren JL, Chen Y, Cui YF, Chen J*, Liu YS*. TSPAN4 influences glioblastoma progression through regulating EGFR stability. iScience. 2024 Volume 27, Issue 8

13.Wang R#, Yu YF#, Yu WR#, Sun SY, Lei YM, Li YX, Lu CX, Zhai JN, Bai FR, Ren FZ, Huang JQ*, Chen J*. Immunomodulatory Effects of Probiotics, Prebiotics, and Postbiotics on B-cell-related Diseases. The Journal of Nutrition. 2024 (In press)

14. Chen J, Xue YC*. Emerging roles of non-coding RNAs in epigenetic regulation. Science China Life Sciences. 2016, 59(3):227-235.

15. Chen J, Fu R, Cui Y, Pan JR, Li YS, Zhang XX, Evans Sylvia M, Cui S, Liu JL*. LIM-homeodomain transcription factor Isl-1 mediates kisspeptin’s effect on insulin secretion in mice. Molecular Endocrinology. 2014 Aug; 28(8):1276-90.

16. Chen J, Fu R, Cui Y, Li YS, Pan JR, Liu JL, Luo HS, Yin JD, Li DF*, Cui S*. LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice. Journal of Biological Chemistry. 2013 Apr 26;288(17):12395-405.

17. Zhao HL, Cai ZK, Rao J, Wu D, Ji L, Ye R, Wang D, Chen J, Cao CC, Hu NJ, Shu T, Zhu P, Wang JW, Zhou X, Xue YC. SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis. Molecular Cell. 2024 Feb 1;84(3):490-505.e9

18. Liang L, Cao CC, Ji L, Cai ZK, Wang D, Ye R, Chen J, Yu XH, Zhou J, Bai ZB, Wang RY, Yang XG, Zhu P, Xue YC*. Complementary Alu sequences mediate enhancer-promoter selectivity. Nature. 2023 Jul;619(7971):868-875

19. Cai ZK, Cao CC, Ji L, Ye R, Wang D, Xia C, Wang S, Du ZC, Hu NJ, Yu XH, Chen J, Wang L,Yang XG, He SM, Xue YC*. RIC-seq for global in situ profiling of RNA - RNA spatial interactions. Nature. 2020, 582(7812):432-437.

20. Cao CC, Cai ZK, Xiao X, Rao J, Chen J, Hu NJ, Yang MN, Xing XR, Wang YL, Li MM, Zhou B, Wang XX, Wang JW*, Xue YC*. The architecture of the SARS-CoV-2 RNA genome inside virion. Nature Communications. 2021, 12(1):3917.

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