2022.10-至今：中国农业大学，优秀人才引进，副教授

2019.01-2022.09：中国科学院生物物理研究所，副研究员

2015.05-2018.12：中国科学院生物物理研究所，助理研究员

2009.09-2015.01：中国农业大学，动物生理学，理学博士

2005.09-2009.06：河北师范大学，生命科学学院，生物科学，理学学士

围绕B细胞相关免疫缺陷疾病及其转化医学开展研究，重点关注B细胞抗体免疫应答的稳态维持和调节机制；利用前沿多组学技术探究免疫缺陷疾病的致病机制，挖掘免疫缺陷疾病治疗的新靶点及营养干预策略。

1.    国家乳业技术创新中心横向课题，2024.01-2024.12，248万，主持

2.    国家重点研发计划课题，2023.12-2027.12，390万，主持

3.    国家乳业技术创新中心创新能力建设重点项目，2023.12-2025.12, 70万，主持

4.    国家自然科学基金面上项目，2020.01-2023.12，58万，主持

5.    北京市自然科学基金面上项目，2018.01-2020.12， 20万，主持

6.    国家自然科学基金青年科学基金，2017.01-2019.12， 22万，主持

7.    中国农业大学基本科研业务费，2023.1.1-2023.10.30，13万，主持

8.     中国农业大学科研创新专项基金，2012.01-2013.12， 4万，主持

1. Han TS, Wei W, Jiang WB, Geng YD, Liu ZJ, Yang RM, Jin CR, Lei YT, Sun XY, Xu JX, Zhou N, Chen J^*, Sun CH^*. The Future landscape and framework of precision nutrition. Engineering. (2024) (In press)

2. Zhang YG, Lei YM, Dong YB, Chen SW, Sun SY, Zhou FE, Zhao ZW, Chen BN, Wei L^*, Chen J^*, Meng ZJ^*. Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases. Pharmacology & Therapeutics. 2024 Jan 253, 108576

3. Sun SY, Fang B, Wang R, Ren FZ, Chen J^*. ERV: a promising new target for lung adenocarcinoma treatment. Science bulletin. 2023 Aug 19;S2095-9273 (23) 00562-5

4. Sun LJ, Lv Z, Chen XX, Ye R, Tian S, Wang CF, Xie XM, Yan L, Yao XH, Cui S, Chen J^*, Liu JL^*. SRSF1-mediated alternative splicing of Tial1/Tiar is essential for homing and self-renewal in mouse spermatogonial stem cells. Elife. 2023, 12:RP89316

5. Sun LJ^#, Chen J^#, Ye R, Lv Z, Chen XX, Xie XM, Li YH, Wang CF, Lv PB, Yan L, Tian S, Yao XH, Chen C, Cui S, Liu JL^*. SRSF1 is crucial for male meiosis through alternative splicing during homologous pairing and synapsis in mice. Science bulletin. 2023 Jun 15;68(11):1100-1104 (Cover story and Research highlight)

6. Chen J, Cai ZK, Bai MZ, Yu XH, Zhang C, Cao CC, Hu XH, Wang L, Su RB, Wang D, Wang L, Yao YP, Ye R, Hou BD, Yu Y, Yu SY, Li JS, Xue YC^*. The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. Cell Research. 2018, Aug 24; 28:981-995. (Cover story and Research highlight) 

7. Chen J, Xue YC^*. Emerging roles of non-coding RNAs in epigenetic regulation. Science China Life Sciences. 2016, 59(3):227-235.

8. Zhao HL, Cai ZK, Rao J, Wu D, Ji L, Ye R, Wang D, Chen J, Cao CC, Hu NJ, Shu T, Zhu P, Wang JW^*, Zhou X^*, Xue YC^*. SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis. Molecular cell. 2024 Feb 1;84(3):490-505

9. Liang L, Cao CC, Ji L, Cai ZK, Wang D, Ye R, Chen J, Yu XH, Zhou J, Bai ZB, Wang RY, Yang XG, Zhu P, Xue YC^*. Complementary Alu sequences mediate enhancer-promoter selectivity. Nature 2023, 619(7971), 868-875

10. Cai ZK, Cao CC, Ji L, Ye R, Wang D, Xia C, Wang S, Du ZC, Hu NJ, Yu XH, Chen J, Wang L,Yang XG, He SM, Xue YC^*. RIC-seq for global in situ profiling of RNA - RNA spatial interactions. Nature. 2020, 582(7812):432-437.

11. Cao CC, Cai ZK, Xiao X, Rao J, Chen J, Hu NJ, Yang MN, Xing XR, Wang YL, Li MM, Zhou B, Wang XX, Wang JW^*, Xue YC^*. The architecture of the SARS-CoV-2 RNA genome inside virion. Nature communications. 2021, 12(1):3917.

12. Chen J, Fu R, Cui Y, Pan JR, Li YS, Zhang XX, Evans Sylvia M, Cui S, Liu JL^*. LIM-homeodomain transcription factor Isl-1 mediates kisspeptin’s effect on insulin secretion in mice. Molecular Endocrinology. 2014 Aug; 28(8):1276-90.

13. Chen J, Fu R, Cui Y, Li YS, Pan JR, Liu JL, Luo HS, Yin JD, Li DF^*, Cui S^*. LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice. J Biol Chem. 2013 Apr 26;288(17):12395-405.

14. Zhang N, Lin JK, Chen J, Liu XF, Liu JL, Luo HS, Li YQ, Cui S^*. MicroRNA 375 mediates the signaling pathway of corticotropin-releasing factor (CRF) regulating pro-opiomelanocortin (POMC) expression by targeting mitogen-activated protein kinase 8. J Biol Chem. 2013 Apr 12;288(15):10361-73. 

15. Li YS, Pan JR, Wei C, Chen J, Liu Y, Liu JL, Zhang XX, Evans Sylvia M, Cui Y^* and Cui S^*. LIM homeodomain transcription factor Isl1 directs normal pyloric development via targeting Gata3. BMC Biology. 2014 12(1):25.