2005-2009 武汉大学生命科学学院,本科
2009-2014 中国科学院营养科学研究所/华东理工大学, 硕博连读
2014-2016 浙江大学转化医学研究院,助理研究员
2016-2020 中国农业大学食品营养与人类健康高精尖创新中心,岗位科学家
2020-2022 中国农业大学理学院,博士后
2022 至今 中国农业大学营养与健康系,副教授
主要研究方向为微量营养素稳态与代谢性疾病。通过人群流行病学及分子生物学等手段,发现微量营养素的稳态调控机制及其失衡对常见慢病的影响,开发具有针对性的营养干预策略。
2024.1 - 2027.12,国家自然基金面上项目,《肝窦内皮细胞mTORC2-FoxO1轴调控机体铁感应的机制研究》,项目负责人
2023.12 - 2027.12,国家重点研发计划,《灾害或极端条件下普通及特殊受灾人群、救援人群营养代谢特征研究》,子课题任务负责人
2016.1 - 2018.12,国家自然基金青年科学基金,《铁稳态代谢中Hepcidin负调控因子的功能机制研究》,项目负责人。
1. Xu T,# Zhang X,# Zhao W, Shi J, Wan S, Zhang Y, Hao Y, Sun M, He J, Jiang L, Wang H, Gao H*, Luo J*, Luo Y*, An P*. Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis. Blood, 2024; 144, 1314–1328. (* Corresponding author) 封面论文
Editorial: Yien, Y.Y. What does the FOX(O) say? High iron: hepcidin! Blood 2024; 144, 1243–1245.
2. Zhao W, # Chen J, # Xia Y, # Wei Z, Wan S, Guo H, Hao Y, Jiang W, Zhang H, Ren F*, An P*, Luo Y*, Luo J*. Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets. Science Bulletin, 2024. Doi: 10.1016/j.scib.2024.07.001 (* Corresponding author)
3. An P,# Wan S,# Wang L, Xu T, Xu T, Wang Y, Liu J, Li K, Wang X,* He J,* Liu S*. Modifiers of the Effects of Vitamin D Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Engineering, 2024;42;99-107. (# Co-first author)
4. Liu S, An P. Untangling the uncertainty in B vitamins for stroke prevention: folic acid fortification, dosage, and their interaction? The American Journal of Clinical Nutrition 119, 593–594 (2024).
5. Luo Y, # Luo J, # An P, # Zhao Y,# Zhao W,# Fang Z, Xia Y, Zhu L, Xu T, Zhang Xu, Zhou S, Yang M, Li J, Zhu J, Liu Y, Li H, Gong M, Liu Y, Han J, Guo H,# Zhang H,* Jiang W,* Ren F*. The AP-1 complex governs a vascular degenerative transcriptional program in smooth muscle cells to trigger aortic dissection and rupture. European Heart Journal (2023). (# Co-first author)
- Editorial: Miteva, K. On target inhibition of vascular smooth muscle cell phenotypic transition underpins TNF–OXPHOS–AP-1 as a promising avenue for anti-remodelling interventions in aortic dissection and rupture. European Heart Journal 45, 306–308 (2023).
6. Wan S, He J,* Simoes EJ, Mechanick JI, Wu WC, An P, Liu S. Chromium supplementation to reduce cardiometabolic risk factors. JACC Advances, 2, 100729 (2023).
7. Wang X, # Ji Y, # Qi J, Zhou S, Wan S, Fan C, Gu Z, An P, * Luo Y, * Luo J*. Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells. Cell Death & Disease, 14, 508 (2023). (* Corresponding author)
8. An P,# Wan S,# Luo Y, Luo J, Zhang X, Zhou S, Xu T, He J, Mechanick JI, Wu WC, Ren F,* Liu S*. Micronutrient Supplementation to Reduce Cardiovascular Risk. Journal of the American College of Cardiology 80, 2269–2285 (2022). (# Co-first author)
- Editorial: Gormaz JG, Carrasco R. Antioxidant Supplementation in Cardiovascular Prevention: New Challenges in the Face of New Evidence. J Am Coll Cardiol 80, 2286–2288 (2022).
9. Zhang J, Liu Z, Chen R, Ma Q, Lyu Q, Fu S, He Y, Xiao Z, Luo Z, Luo J, Wang X, Liu X, An P,* Sun W*. A MALDI-TOF mass spectrometry-based haemoglobin chain quantification method for rapid screen of thalassaemia. Annals of Medicine, 54, 293–301 (2022). (* Corresponding author)
10. Xu T, Zhang X, Liu Y, Wang H, Luo J,* Luo Y,* An P*. Effects of dietary polyphenol supplementation on iron status and erythropoiesis: a systematic review and meta-analysis of randomized controlled trials. The American Journal of Clinical Nutrition, 114, 780–793 (2021). (* Corresponding author)
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