2022.11–至今 中国农业大学 营养与健康系 博士后

2018.09–2022.06 中国农业大学 工学博士

2015.09–2018.06 南京财经大学 工学硕士

2011.09­–2015.06 徐州工程学院 工学学士

1．天然产物与功能食品

2. 血管衰老与平滑肌表型转化

国家重点研究计划：水产品营养功效因子结构表征与功能解析 参与

国家自然基金面上项目：菜籽蛋白源ACE-肾素双重抑制肽稳定性及机制研究 参与

1. Yijie Yang, Bo Wang, Bo Li^*. Structural Requirement of Casein Peptides for Transcytosis through the Caco-2 Cell Monolayer: Hydrophobicity and Charge Property Affect the Transport Pathway and Efficiency. Journal of Agricultural and Food Chemistry. 2019, 67(42): 11778-11787.

2. Yijie Yang, Bo Li^*. Novel peptide motifs containing Asp-Glu-Gly targets P₂Y₁₂ and thromboxane A2 receptor to inhibit platelet aggregation and thrombus formation. Journal of Agricultural and Food Chemistry. 2022, 70, 785-793.

3. Yijie Yang, Bo Li^*. A collagen-derived oligopeptide from Salmo Salar collagen hydrolysates restrains atherogenesis in ApoE^-/- mice via targeting P₂Y₁₂ receptor. Molecular Nutrition and Food Research. 2022, 2200166.

4. Yijie Yang, Qi Tian, Bo Li^*. Structural Insights on Hyp-Gly-Containing Peptides as Antiplatelet Compounds through Topomer CoMFA and CoMSIA Analysis. Foods. 2023, 12, 777.

5. Yijie Yang, Hongdong Song, Bo Wang, Qi Tian and Bo Li^*. A novel di-peptide Met-Glu from collagen hydrolysates inhibits platelet aggregation and thrombus formation via regulation of Gq-mediated signaling. Journal of Food Biochemistry. 2020.44(9), e13352.

6. Yijie Yang, Bo Wang, Qi Tian and Bo Li^*. Purification and Characterization of Novel Collagen Peptides against Platelet Aggregation and Thrombosis from Salmo Salar. ACS Omega. 2020, 5(32), 19995-20003.

7. Yijie Yang, Haiyan He, Fengzhang Wang, Xingrong Ju, Jian Yuan, Lifeng Wang, Rotimi E.Aluko and Rong He^*.Transport of angiotensin converting enzyme and renin dual inhibitory peptides LY, RALP and TF across Caco-2 cell monolayers. Journal of Functional Foods. 2017. 35, 303-314.

8. Rong He^*, Yijie Yang, Zhigao Wang, Changrui Xing, Jian Yuan, Lifeng Wang, Chibuike Udenigwe and Xingrong Ju. Rapeseed protein-derived peptides, LY, RALP, and GHS, modulates key enzymes and intermediate products of renin-angiotensin system pathway in spontaneously hypertensive rat. NPJ Science of Food. 2019. 3, 1.

9. Fengzhang Wang, Yijie Yang, Xingrong Ju, Chibuike Udenigwe and Rong He^*. Polyelectrolyte complex nanoparticles from chitosan and acylated rapeseed cruciferin protein for curcumin delivery. Journal of Agricultural and Food Chemistry. 2018. 66, 2685-2693.

10. 王凤章, 杨毅杰, 等. (2017). 菜籽肽的ACE、肾素抑制活性及抗氧化性研究. 中国粮油学报, 32(5), 50-56.

11. 李博，杨毅杰，宋洪东，等. 含有ME序列的一类新型抑制血小板聚集和抗血栓形成寡肽. 发明专利，已授权

12. 李博，田淇，杨毅杰，等. 含有Hyp-Gly序列的一类抗血小板和抗血栓功能的寡肽. 发明专利，已授权