2024.11-至今 中国农业大学营养与健康系 副教授/研究员
2022.3-2024.10 清华大学化学系 博士后、助理研究员
2021.7-2022.2 南昌大学医学部 副教授
2018.9-2021.6 清华大学化学系 分析化学 理学博士
2017.1-2018.8 清华大学化学系 科研助理
2014.9-2017.1 东北大学理学院 物理化学 理学硕士
2010.9-2014.7 江西科技师范大学 应用化学 理学学士
学术兼职
中国医药生物技术协会药物分析技术分会 委员
中国检验检测学会青委会 理事
北京理化分析测试技术学会青委会 理事
中国民族医药学会方药量效研究分会 常务理事
中国中药协会大品种开发与培育专业委员会 委员
《J Pharm Anal》、《Exploration》、《MedMat》 青年编委
学术奖励与荣誉
2024 中国科协党校青年科技领军人才“领航计划”
2022 国家博士后创新人才支持计划(药物分析学)
2023 北京市科协青年人才托举工程
2023 北京市科协创新争先科技工作者
2023 清华大学化学系卓越博士后
2022 清华-北大生命科学联合中心特等博士后
2018 辽宁省优秀硕士毕业论文
研究领域
主要研究方向为药物分析,微流控芯片,生命分析与健康
研究概况
以微流控技术和纳米技术为基础,融合药物分析与生命分析、整合药效物质分析与药理效应分析评价的战略,开展了以下2个方面的研究工作:1)开发基于微纳技术的微流控分析与检测新方法,发展了基于微流控技术的药物质量分析与效应评价新方法。2)构建基于微纳技术的纳米酶药物递送与分析新体系,发展了药物分析研究新领域,提出了“High-entropy nanozymes”(高熵纳米酶)的新概念。近年来发表SCI论文50余篇,在Adv. Mater., Adv. Funct. Mater., Adv. Sci., Small., TrAC.和Anal. Chem.等国际知名期刊以第一作者和共同通讯作者发表IF>10的高水平SCI论文16篇,其中ESI高被引论文2篇,论文总被引用3200余次,H指数32,授权发明专利9项。
1. 中国农业大学青年研究员项目,项目编号:2024QNYJY143,2024.11-2029.11,主持。
2. 国家重点研发计划子课题,项目编号:2023YFC3504401,2024.1-2026.12,主持。
3. 国家自然科学基金青年基金项目,项目编号:82304442,2024.1-2026.12,主持。
4. 北京市科协青年人才托举工程,项目编号:BYESS2023166,2023.1-2025.12, 主持。
5. 国家博士后创新人才支持计划,项目编号:BX20220160,2022.3-2024.3,主持。
6. 中国博士后科学基金面上项目,项目编号:2022M711779,2022.3-2024.3,主持。
1. Yongjian Ai‡*, Meng-Qi He‡, Hua Sun, Wanting Hu, Xinyue Zhang, Hong-bin Sun, Qionglin Liang*, Ultra-small high-entropy alloy nanoparticles: efficient nanozyme for enhancing tumor photothermal therapy. Advanced Materials, 2023, 35, 2302335.
2. Meng-Qi He, Yongjian Ai*, Wanting Hu, Liandi Guan, Mingyu Ding, Qionglin Liang*, Recent advances of seed-mediated growth of metal nanoparticles: from growth to applications. Advanced Materials, 2023, 35, 2211915.
3. Yongjian Ai, Ze-Nan Hu, Xiaoping Liang*, Hong-bin Sun, Hongbo Xin*, Qionglin Liang*. Recent advances in nanozymes: from matters to bioapplications. Advanced Functional Materials, 2022, 32, 2110432.
4. Yongjian Ai, Hua Sun, Zhuxian Gao, Chenlong Wang, Liandi Guan, Yu Wang, Yanping Wang, Huiying Zhang, Qionglin Liang*. Dual enzyme mimics based on metal-ligand cross-linking strategy for accelerating ascorbate oxidation and enhancing tumor therapy. Advanced Functional Materials, 2021, 31, 2103581.
5. Jianghua Zhang‡, Yongjian Ai‡, Jiajing Wu, Daile Zhang, Yun Wang, Zhongmin Feng, Hong-Bin Sun*, Qionglin Liang, Ting Sun*, Yang Yang*. Nickel-catalyzed synthesis of three-dimensional edge-curled graphene for high-performance lithium-ion batteries. Advanced Functional Materials, 2020, 30, 1904645.
6. Yongjian Ai, Zenan Hu, Lei Liu, Junjie Zhou, Yang Long, Jifan Li, Mingyu Ding, Hong-Bin Sun*, Qionglin Liang*. Magnetically hollow Pt nanocages with ultrathin walls as a highly integrated nanoreactor for catalytic transfer hydrogenation reaction. Advanced Science, 2019, 6, 1802132.
7. Cai-Shi Lin‡, Meng-Qi He‡, Meng-Ying An, Qi-Hang Zhao, Zhou-Hang Zhang, Ke-Yu Deng, Yongjian Ai*, Hong-Bo Xin*. Ultra-small copper-based multienzyme-like nanoparticles protect against hepatic ischemia-reperfusion injury through scavenging reactive oxygen species in mice, Small, 2024, 20, 2403313.
8. Xinmei Xu‡, Suet Cheung‡, Xiaomeng Jia, Gang Fan, Yongjian Ai*, Yi Zhang*, Qionglin Liang*. Trends in organ-on-a-chip for pharmacological analysis, TrAC-Trends in Analytical Chemistry, 2024, 180, 117905.
9. Imamdin Chandio, Yongjian Ai*, Lei Wu, Qionglin Liang*, Recent progress in MOFs-based nanozymes for biosensing, Nano Research, 2024, 17, 39–64.
10. Meng-Qi He, Yongjian Ai*, Wanting Hu, Xiaomeng Jia, Lei Wu, Mingyu Ding, Qionglin Liang*. Dual-functional capping agent mediated-transformation of silver nanotriangles to silver nanoclusters for dual-mode biosensing, Analytical Chemistry, 2023. 95, 6130–6137.
11. Mengying An‡, Mengqi He‡, Caishi Lin, Yuebo Wu, Yongjian Ai*, Hongbo Xin*, Qionglin Liang*. Recent progress of nanozymes with different spatial dimensions for bioanalysis. Materials Today Nano, 2023, 22, 100330.
12. Yongjian Ai, Hua Sun, Chenlong Wang, Wenchen Zheng, Qiang Han, Qionglin Liang*. Tunable assembly of organic-inorganic molecules into hierarchical superstructures as ligase mimics for enhance tumors photothermal therapy. Small, 2022, 18, 2105304.
13. Yongjian Ai‡, Meng-qi He‡, Chengxian Wan, Hua Lu, Hongbo Xin*, Yitao Wang*, Qionglin Liang*, Nanoplatform-based reactive oxygen species scavengers for therapy of ischemia-reperfusion injury. Advanced Therapeutics, 2022, 5, 2200066.
14. Yongjian Ai, Jinzhi You, Jianyi Gao, Jiaping Wang, Hong-bin Sun, Mingyu Ding, Qionglin Liang*. Multi-shell nanocomposites based multienzyme mimetics for efficient intracellular antioxidation. Nano Research, 2021, 14, 2644–2653.
15. Yongjian Ai, Ruoxiao Xie, Jialiang Xiong, Qionglin Liang*. Microfluidics for biosynthesizing: from droplets and vesicles to artificial cells. Small, 2020, 16, 1903940.
16. Yongjian Ai, Feng Zhang, Chenlong Wang, Ruoxiao Xie, Qionglin Liang*. Recent progress in lab-on-a-chip for pharmaceutical analysis and pharmacological/toxicological test. TrAC-Trends in Analytical Chemistry, 2019, 117, 215–230.
17. Yongjian Ai, Mengqi He, Feng Zhang, Yang Long, Yunzheng Li, Qiang Han, Mingyu Ding, Hong-Bin Sun*, Qionglin Liang*. Metallo-supramolecular polymer engineered porous carbon framework encapsulated stable ultra-small nanoparticles: a general approach to construct highly dispersed catalysts. Journal of Materials Chemistry A, 2018, 6, 16680–16689.
18. Yongjian Ai, Lei Liu, Cheng Zhang, Li Qi, Mengqi He, Zhe Liang, Hong-Bin Sun*, Guoan Luo, Qionglin Liang*. Amorphous flowerlike goethite FeOOH hierarchical supraparticles: superior capability for catalytic hydrogenation of nitroaromatics in water. ACS Applied Materials & Interfaces, 2018, 10, 32180–32191.
19. Yongjian Ai, Zenan Hu, Zixing Shao, Li Qi, Lei Liu, Junjie Zhou, Hong-Bin Sun*, Qionglin Liang*. Egg-like magnetically immobilized nanospheres: a long-lived catalyst model for the hydrogen transfer reaction in a continuous-flow reactor. Nano Research, 2018, 11, 287–299.
20.Hong-Bin Sun*, Yongjian Ai, Dong Li, Zhike Tang, Zixing Shao, Qionglin Liang*. Bismuth iron oxide nanocomposite supported on graphene oxides as the highly efficient, stable and reusable catalysts for the reduction of nitroarenes under continuous flow conditions. Chemical Engineering Journal, 2017, 314, 328–335.
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